Musculoskeletal Complications of Cancer and its Treatments
In this webinar Dr. Bonetto presents evidence that bone preservation directly impacts muscle size and function in cachexia, thus also contributing to unraveling novel pathogenetic mechanisms and opening new avenues for treatment.
How to calibrate an Aurora Scientific High Speed Length Controller using HVSL
Our 315D & 322D models of High-Speed Length Controllers are routinely used by researchers studying small tissue samples such
Biomechanical Properties of GI Smooth Muscle
Image courtesy of Siri et al. (2019). Disorders like gastroparesis, gastroesophageal reflux disease (GERD), and
Treating Spinal-Muscle Conditions
Featured image courtesy of Bilchak et al. (2021). Spinal disruption can lead to serious
Restoring Volumetric Muscle Loss with Hydrogels
Featured image courtesy of Costantini et al. (2021). Even though skeletal muscle can quickly
Tips and Tricks for using the 1400A Permeabilized Fiber System
Our 1400A permeabilized fiber system is commonly used to investigate the active and passive properties of skinned, or de-membranized
Cancer, Chemotherapy, and Muscle Weakness
Featured Image courtesy of J.R. Huot et al. (2021). Chemotherapy can increase the survival
Aging and Skeletal Muscle Plasticity
WEBINAR: Join Sue Bodine, PhD for a deep dive into her research focused on the decline in muscle mass with aging and the role that innervation plays in muscle atrophy.
Measuring the Mechanical Properties of Engineered Tissue Constructs
Tissue engineering is an important field of regenerative medicine for tissue repair after damage caused by
A Step Further: Customizing the 3-in-1 Whole Animal System
In scientific experimentation, the products available do not always fit the model perfectly. Many labs build their own devices
Tips and Tricks for Troubleshooting the 300C Dual-Mode Muscle Levers
Here we will cover some of the more common issues that researchers encounter when using our Dual-Mode Lever System. If
Cell Deformation and Mechanical Force Stimulation to Study Cellular Structure and Function
Cells are constantly experiencing mechanical forces, whether from the external environment, cells around them, or internal physiological changes. These
A Step Further: Augmented Muscle Mechanics Measurements
In scientific experimentation, the products available do not always fit the model perfectly. Many labs end up building their
Tips and Tricks for Using the 1600A Permeabilized Myocyte System
The 1600A permeabilized myocyte system is commonly used to investigate the active and passive properties of de-membranized cardiac myocytes. This system
Diaphragm Muscle Weakness with Age and Sepsis
Muscle weakness can be caused by a number of factors and disorders, and naturally declines with age. This publication review explores diaphragmatic contractile function in two different studies using mice.
Unconventional and Invaluable, Unique Models in Muscle Physiology
Aurora Scientific has helped thousands of laboratories perform functional, contractile testing of muscle for
Insights Into the Pathways Involved in Muscle Aging
Muscle aging has several underlying factors, including decreased numbers of muscle stem cells, mitochondrial dysfunction, a decline in protein quality
Advancements in Musculoskeletal Simulations for in vitro Muscle Physiology Research
Experimentation in vitro enables physiologists to control neuromuscular stimulation and strain patterns to help determine how the nervous system modulates
All Creatures Great and Small – Part 2.
Aurora Scientific has helped thousands of laboratories perform functional, contractile testing of muscle for nearly 25 years. Though most
Tips and Tricks for Measuring Muscle Function in-situ
Aurora Scientific’s 1300A/1305A Isolated Muscle systems have been relied upon by researchers worldwide for nearly 20 years. Though the systems
Optogenetics and Muscle Activity; the Inhibitory and Stimulatory Effects of Light in Neuromuscular Research Applications
Neuromuscular disorders can have severe symptoms that effect the ability to complete even simple daily activities. While their root
Case Studies in the Assessment of Skeletal Muscle Function in Rodent Models of Cancer Cachexia
The maintenance of muscle mass is critical in the fight against cancer. Reduced muscle function is associated with a
A Look at Bone-Muscle Crosstalk From in-vivo and in-vitro Perspectives
The bone-muscle interface can be thought of as a lever system: the joint acts as the fulcrum while the
Improved Methods & Models for Comparative Muscle Physiology
Beyond the increasingly diverse list of animal models used to to study the link between genotype and phenotype, clever