Cut and Paste of Myosin Binding Protein-C in Striated Muscles
Dr. Samantha Harris discusses the development of three new mouse models in her lab, engineered to target and replace specific myosin binding protein-C paralogs in muscle fibers and impact of their mutations on skeletal and cardiac muscle diseases.
Mechanical Control of Relaxation Using Intact Cardiac Trabeculae
Melissa Bukowski and colleagues describe and demonstrate a method to measure mechanical control of relaxation or the strain dependence of muscle relaxation in rodent cardiac trabecula.
Analyzing Cardiac Tissue Function
The following publication review showcases recent studies that use Aurora Scientific equipment to make advances in the field of biomechanics.
Excellence, Innovation, and Collaboration: Key Research at the MHRC
This past April, we partnered with InsideScientific and the Muscle Health Research Centre (MHRC) at York University, a one-of-a-kind facility that fosters an interdisciplinary approach to the study of muscle physiology. We interviewed three keystone researchers who are shaping the future of skeletal muscle health: David Hood, PhD, Peter Backx, PhD, and Ali Abdul-Sater, PhD.
Excellence, Innovation, and Collaboration: Student Research at the MHRC
This past April, we partnered with InsideScientific and the Muscle Health Research Centre (MHRC) at York University, a one-of-a-kind facility that fosters an interdisciplinary approach to the study of muscle physiology. We had the privilege of interviewing a number of faculty and students to highlight their research, as well as the opportunities provided to them by the MHRC.
Muscle Function in Diabetes and Heart Failure
This publication review takes a look at muscle function in the context of diabetes and heart failure, and how these mechanistic findings can help develop targeted therapies in the future.
Investigating a Novel Regulator of Atrial Contractility
Dr. David Barefield gives an in-depth discussion on his research investigating the role of the MyBP-HL protein in atrial dysfunction.
Cardiac Biophysics
Cardiac biophysics is a necessary component for understanding cardiac disease and dysfunction. This publication review explores recent publications that investigate mechanical and biophysical properties of cardiac muscle.