Molecular Deep Dives in Force Production

Muscle Physiology, Publication Review|

As we launch full force into 2024, studies exploring the molecular underpinnings of force production in mice have blazed the trail of functional muscular research. From calcium dynamics during muscle contraction, to muscle impairments in myotonic dystrophy, and the effects of running on muscle mass in a dystrophic mouse model, January's novel insights into muscle function and regulation have important implications on our understanding of muscle physiology and health.

Best of 2023: Across Countries and Applications

Materials Science, Muscle Physiology, Olfaction & Plume Tracking, Publication Review|

2023 has proved to be a particularly fruitful year for scientific discovery, with a multitude of pioneering studies spanning continents and disciplines. From the intricate workings of muscle physiology in Switzerland to the nuanced understanding of migraine mechanisms in the USA, the discernment of mosquito olfactory processing in India, and the innovative strides in sustainable materials science in Germany and Austria, this year's research highlights embody the spirit of global collaboration and scientific ingenuity. We hope that, by highlighting the multitude of ways our instruments provide precise and reliable data, future and current researchers can draw inspiration for new and innovative ways to collaborate across borders.

Renewed Interests: Harnessing Engineered Constructs to Explore Novel Strategies in Regenerative Medicine

Cardiovascular, Materials Science, Muscle Physiology, Publication Review|

Tissue engineering is at the forefront of regenerative medicine, offering immense promise for restoring or enhancing the function of impaired tissues and organs. While tissue constructs remain costly in clinical settings, their use as a research tool holds vast potential for drug discovery, aiding and expediting the screening of drug candidates. In this publication review, we will discuss three recent publications leveraging specialized equipment from Aurora Scientific to advance the innovative field of engineered tissue constructs.

  • Cancer Cachexia-Induced Muscle Atrophy

Cancer Cachexia-Induced Muscle Atrophy

Muscle Physiology, Publication Review|

Cancer cachexia is a muscle wasting syndrome that is associated with certain cancers, but most commonly with advanced malignancies. This syndrome arises as a result of tumor-induced metabolic changes, causing the body to break down skeletal muscle and adipose tissue in response to nutritional deficiencies. These changes manifest as severe weight loss, anorexia, asthenia, and anemia, impairing the patient's capacity to tolerate infections, chemotherapy, and radiation treatments (Dhanapal et al., 2022). While research characterizing the multifactorial origins of this syndrome is still ongoing, three recent publications featuring our scientific equipment have made notable advances in the current understanding of this muscle wasting disease, and are discussed in this publication review.

  • Integrating Patient Engagement and Trainee Development in Pre-Clinical Research

Integrating Patient Engagement and Trainee Development in Pre-Clinical Research

Events, Live Webinars, Muscle Physiology, On-Demand Webinars, Videos|

Christopher Perry, PhD discusses how his laboratory aims to discover mechanisms by which metabolic dysfunction causes muscle weakness and apply these findings to develop new therapies for muscle disorders. Homira Osman, PhD will provide a particular focus on leveraging scientific findings for practice and policy and linking trainees with patient communities.

  • Excellence, Innovation, and Collaboration

Excellence, Innovation, and Collaboration: Key Research at the MHRC

Cardiovascular, Interviews, Muscle Physiology, News, Videos|

This past April, we partnered with InsideScientific and the Muscle Health Research Centre (MHRC) at York University, a one-of-a-kind facility that fosters an interdisciplinary approach to the study of muscle physiology. We interviewed three keystone researchers who are shaping the future of skeletal muscle health: David Hood, PhD, Peter Backx, PhD, and Ali Abdul-Sater, PhD.

  • MRHC Student Interviews

Excellence, Innovation, and Collaboration: Student Research at the MHRC

Cardiovascular, Interviews, Muscle Physiology, News, Videos|

This past April, we partnered with InsideScientific and the Muscle Health Research Centre (MHRC) at York University, a one-of-a-kind facility that fosters an interdisciplinary approach to the study of muscle physiology. We had the privilege of interviewing a number of faculty and students to highlight their research, as well as the opportunities provided to them by the MHRC.

  • Excellence, Innovation, and Collaboration: A Day at the MHRC with Arthur Cheng

Excellence, Innovation, and Collaboration: A Day at the MHRC with Arthur Cheng

Interviews, Muscle Physiology, News, Videos|

Interviewing Dr. Arthur Cheng at the Muscle Health Research Centre (MHRC), York University, an innovative research centre that facilitates the interdisciplinary study of muscle biology and the importance of skeletal muscle to the overall health and well-being of Canadians. Dr. Cheng's lab primarily investigates the mechanisms of skeletal muscle weakness and fatigue, and focuses on how calcium handling affects these mechanisms.