Excellence, Innovation, and Collaboration: A Day at the MHRC with Arthur Cheng
Interviewing Dr. Arthur Cheng at the Muscle Health Research Centre (MHRC), York University, an innovative research centre that facilitates the interdisciplinary study of muscle biology and the importance of skeletal muscle to the overall health and well-being of Canadians. Dr. Cheng's lab primarily investigates the mechanisms of skeletal muscle weakness and fatigue, and focuses on how calcium handling affects these mechanisms.
Muscle Function in Diabetes and Heart Failure
This publication review takes a look at muscle function in the context of diabetes and heart failure, and how these mechanistic findings can help develop targeted therapies in the future.
Excellence, Innovation, and Collaboration: A Day at the MHRC with Chris Perry
Interviewing Dr. Christopher Perry at the Muscle Health Research Centre (MHRC), York University, an innovative research centre that facilitates the interdisciplinary study of muscle biology and the importance of skeletal muscle to the overall health and well-being of Canadians. Dr. Perry's lab studies metabolic dysregulation in murine models of muscle weakness disorders.
Talking Real Science with Chris Perry
Christopher Perry, PhD, an Associate Professor at York University with the School of Kinesiology & Health Science joined us to talk in detail about his career path that led him to study regulation of skeletal muscle metabolism. As a dedicated customer, Chris specifically highlights how the 1300A 3-in-1 Whole Animal System helps achieve his research goals.
Attenuating Muscle Disease Pathology
This publication review discusses how Aurora Scientific muscle physiology products are used in muscular dystrophy preclinical research.
Mitochondrial Bioenergetics and Muscle Function
Highlighted in this publication review are systems available from Aurora Scientific that have aided studies of mitochondrial bioenergetics and muscle function in various research areas, including chronic kidney disease (CKD), sarcopenia, and chronopharmacology.
Myofilament Mechanics in Cardiac and Skeletal Muscle
This publication review highlights how Aurora Scientific offers technologies and instruments for facilitating mechanistic studies.
Modelling Exercise-Induced Muscular Changes Using Dynamic Contractions
This publication review highlights how some of our instruments have been used to study the morphological characteristics and function of muscle, as well as myocellular signaling, in rodent models of exercise.
Mitigating Neuromuscular Deficits
This publication review highlights how several researchers have recently employed our instruments and technologies to better understand these mechanisms and uncover new therapeutic avenues for a variety of diseases and disorders.
Cardiac Biophysics
Cardiac biophysics is a necessary component for understanding cardiac disease and dysfunction. This publication review explores recent publications that investigate mechanical and biophysical properties of cardiac muscle.
Nerve versus Muscle Stimulation: When to Use?
This technical blog discusses the importance of choosing the correct method to measure hindlimb mechanics in animal models: nerve or muscle stimulation.
Best of 2021: Muscle Physiology
This publication review summarizes some of the best recent articles that fall under our Muscle Physiology category.
Using the 1700A Single Myofibril System – Tips and Tricks
The 1700A single myofibril system (sometimes referred to as the ‘Penguin’) is commonly used to investigate the active and passive properties of single myofibrils.
Laryngeal Muscles in Development and Disease
Courtesy of Glass et al. (2019). The larynx is an organ that sits in the
Musculoskeletal Complications of Cancer and its Treatments
In this webinar Dr. Bonetto presents evidence that bone preservation directly impacts muscle size and function in cachexia, thus also contributing to unraveling novel pathogenetic mechanisms and opening new avenues for treatment.
How to calibrate an Aurora Scientific High Speed Length Controller using HVSL
Our 315D & 322D models of High-Speed Length Controllers are routinely used by researchers studying small tissue samples such
Biomechanical Properties of GI Smooth Muscle
Image courtesy of Siri et al. (2019). Disorders like gastroparesis, gastroesophageal reflux disease (GERD), and
Treating Spinal-Muscle Conditions
Featured image courtesy of Bilchak et al. (2021). Spinal disruption can lead to serious
Restoring Volumetric Muscle Loss with Hydrogels
Featured image courtesy of Costantini et al. (2021). Even though skeletal muscle can quickly
Tips and Tricks for using the 1400A Permeabilized Fiber System
Our 1400A permeabilized fiber system is commonly used to investigate the active and passive properties of skinned, or de-membranized
Cancer, Chemotherapy, and Muscle Weakness
Featured Image courtesy of J.R. Huot et al. (2021). Chemotherapy can increase the survival
Aging and Skeletal Muscle Plasticity
WEBINAR: Join Sue Bodine, PhD for a deep dive into her research focused on the decline in muscle mass with aging and the role that innervation plays in muscle atrophy.
Measuring the Mechanical Properties of Engineered Tissue Constructs
Tissue engineering is an important field of regenerative medicine for tissue repair after damage caused by
A Step Further: Customizing the 3-in-1 Whole Animal System
In scientific experimentation, the products available do not always fit the model perfectly. Many labs build their own devices