Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation.  They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

Featured Publications

Found 30 Results
Title Research Area Disease Model System/Component Year
MYTHO is a novel regulator of skeletal muscle autophagy and integrity Muscle Pathology & Wasting Atrophy
 1300A: 3-in-1 Whole Animal System for Mice 2023
Muscle weakness precedes atrophy during cancer cachexia and is linked to muscle-specific mitochondrial stress Muscle Pathology & Wasting Cachexia
 1300A: 3-in-1 Whole Animal System for Mice 2022
Microdystrophin Gene Addition Significantly Improves Muscle Functionality and Diaphragm Muscle Histopathology in a Fibrotic Mouse Model of Duchenne Muscular Dystrophy Muscle Pathology & Wasting DMD
 1300A: 3-in-1 Whole Animal System for Mice 2023
Intermittent prednisone treatment in mice promotes exercise tolerance in obesity through adiponectin Exercise & Metabolism Obesity
 1300A: 3-in-1 Whole Animal System for Mice 2022
BAG3 Attenuates Ischemia-Induced Skeletal Muscle Necroptosis in Diabetic Experimental Peripheral Artery Disease Molecular Biology and Pharmacology Diabetes
 1300A: 3-in-1 Whole Animal System for Mice 2022
Optimization and construct validity of approaches to preclinical grip strength testing Muscle Pathology & Wasting Aging
 1300A: 3-in-1 Whole Animal System for Mice 2023
Skeletal muscle delimited myopathy and verapamil toxicity in SUR2 mutant mouse models of AIMS Molecular Biology and Pharmacology Myopathy
 1300A: 3-in-1 Whole Animal System for Mice 2023
Efficient precise in vivo base editing in adultdystrophic mice Muscle Pathology & Wasting DMD
 2021
In vivo Measurement of Knee Extensor Muscle Function in Mice Orthopedics Injury
 1300A: 3-in-1 Whole Animal System for Mice 2021
Targeted genome editing in vivo corrects a Dmd duplication restoring wild-type dystrophin expression Muscle Pathology & Wasting DMD
 1300A: 3-in-1 Whole Animal System for Mice 2021
Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α Exercise & Metabolism Dystrophy
 1300A: 3-in-1 Whole Animal System for Mice 2022
Influenza A Virus-Driven Airway Inflammation may be Dissociated From Limb Muscle Atrophy in Cigarette Smoke-Exposed Mice Muscle Pathology & Wasting Atrophy
 1300A: 3-in-1 Whole Animal System for Mice 2022
microRNA‐29a Regulates ADAM12 Through Direct Interaction With ADAM12 mRNA and Modulates Postischemic Perfusion Recovery Molecular Biology and Pharmacology Ischmia/Reperfusion
 1300A: 3-in-1 Whole Animal System for Mice 2022
Optogenetic activation of muscle contraction in vivo Neuromuscular N/A
 2021
Efficient precise in vivo base editing in adultdystrophic mice Muscle Pathology & Wasting DMD
 2021
In vivo Measurement of Knee Extensor Muscle Function in Mice Orthopedics Injury
 2021
Targeted genome editing in vivo corrects a Dmd duplication restoring wild-type dystrophin expression Muscle Pathology & Wasting DMD
 2021
Muscle contraction induces osteogenic levels of cortical bone strain despite muscle weakness in a mouse model of Osteogenesis Imperfecta Orthopedics Musculoskeletal
 1300A: 3-in-1 Whole Animal System for Mice 2020
A novel ex vivo protocol to mimic human walking gait: implications for Duchenne muscular dystrophy Muscle Pathology & Wasting DMD
 1300A: 3-in-1 Whole Animal System for Mice 2020
Specific inhibition of myostatin activation is beneficial in mouse models of SMA therapy Neuromuscular Neurodegenerative
 2019
Parkin overexpression protects from ageing-related loss of muscle mass and strength Muscle Pathology & Wasting Aging
 1300A: 3-in-1 Whole Animal System for Mice 2019
PERK regulates skeletal muscle mass and contractile function in adult mice Muscle Pathology & Wasting Cachexia
 1300A: 3-in-1 Whole Animal System for Mice 2019
Skeletal muscle function during the progression of cancer cachexia in the male ApcMin/+ mouse Muscle Pathology & Wasting Cachexia
 1300A: 3-in-1 Whole Animal System for Mice 2018
Myonuclear accretion is a determinant of exercise-induced remodeling in skeletal muscle Exercise & Metabolism Atrophy
 2019
Xin-deficient mice display myopathy, impaired contractility, attenuated muscle repair and altered satellite cell functionality. Muscle Pathology & Wasting Dystrophy
 1300A: 3-in-1 Whole Animal System for Mice 2015
Single muscle contractile measurements in vivo and in situ. Muscle Pathology & Wasting Dystrophy
 1300A: 3-in-1 Whole Animal System for Mice 2015
Arsenic induces sustained impairment of skeletal muscle and muscle progenitor cell ultrastructure and bioenergetics. Exercise & Metabolism N/A
 1300A: 3-in-1 Whole Animal System for Mice 2014
Early oxidative shifts in mouse skeletal muscle morphology with high‐fat diet consumption do not lead to functional improvements. Exercise & Metabolism Obesity
 1300A: 3-in-1 Whole Animal System for Mice 2014
Neuromuscular Electrical Stimulation as a Method to Maximize the Beneficial Effects of Muscle Stem Cells Transplanted into Dystrophic Skeletal Muscle. Muscle Pathology & Wasting Dystrophy
 1300A: 3-in-1 Whole Animal System for Mice 2013
Resistance Loading and Signaling Assays for Oxidative Stress in Rodent Skeletal Muscle. Exercise & Metabolism Aging
 1300A: 3-in-1 Whole Animal System for Mice 2011
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