Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation.  They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

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Found 29 Results
Title Research Area Model Product Year
Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis Neuromuscular Neurodegenerative
1200A: Isolated Muscle System for Rodents 2023
Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9 Neuromuscular Musculoskeletal
1200A: Isolated Muscle System for Rodents 2023
Clinically relevant mouse models of Charcot–Marie–Tooth type 2S Neuromuscular Neurodegenerative
300C: Dual-Mode Lever System, 605A: Dynamic Muscle Data Acquisition and Analysis System, 701C: Electrical Stimulator 2023
Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms Neuromuscular Musculoskeletal
300C: Dual-Mode Muscle Levers, 701C: Electrical Stimulator, 901D: High-Speed Video Sarcomere Length, 950A: Calcium Fluorescence System, 1300A: 3-in-1 Whole Animal System for Mice 2022
Paraspinal Muscle Contractile Function is Impaired in the ENT1-deficient Mouse Model of Progressive Spine Pathology Neuromuscular Neurodegenerative
901D: High-Speed Video Sarcomere Length 2021
Paraspinal Muscle Contractile Function is Impaired in the ENT1-deficient Mouse Model of Progressive Spine Pathology Neuromuscular Neurodegenerative
901D: High-Speed Video Sarcomere Length 2021
Minocycline Treatment Reduces Mass and Force Output From Fast-Twitch Mouse Muscles and Inhibits Myosin Production in C2C12 Myotubes Neuromuscular Atrophy
615A: Dynamic Muscle Control and Analysis Software 2021
Optogenetic activation of muscle contraction in vivo Neuromuscular N/A
1300A: 3-in-1 Whole Animal System for Mice 2021
Loss of dysferlin or myoferlin results in differential defects in excitation–contraction coupling in mouse skeletal muscle Neuromuscular Dystrophy
950A: Calcium Fluorescence System, 901D: High-Speed Video Sarcomere Length, 701C: Electrical Stimulator 2021
Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy Neuromuscular Neurodegenerative
400B: Force Transducers 2020
Assessing Rat Forelimb and Hindlimb Motor Unit Connectivity as Objective and Robust Biomarkers of Spinal Motor Neuron Function Neuromuscular Neurodegenerative
1305A: 3-in-1 Whole Animal System for Rats 2019
Extrinsic Primary Afferent Neurons Link Visceral Pain to Colon Motility Through a Spinal Reflex in Mice Neuromuscular Neurodegenerative
300C: Dual-Mode Muscle Levers 2019
Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease Neuromuscular Neurodegenerative
2019
Specific inhibition of myostatin activation is beneficial in mouse models of SMA therapy Neuromuscular Neurodegenerative
1300A: 3-in-1 Whole Animal System for Mice 2019
Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease Neuromuscular Neurodegenerative
701C: Electrical Stimulator 2019
Reversible temporally-specific inhibition of muscle using a light-activated chloride channel Neuromuscular Myopathy
300C: Dual-Mode Muscle Levers 2018
Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function. Neuromuscular Cancer
1500A: Isolated Muscle System – Microscope Mountable 2015
Measuring Neuromuscular Junction Functionality in the SOD1G93A Animal Model of Amyotrophic Lateral Sclerosis. Neuromuscular Neurodegenerative
701C: Electrical Stimulator 2015
Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function. Neuromuscular Cancer
801C: Small Intact Muscle Apparatus – Microscope Mountable 2015
Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function. Neuromuscular Cancer
809C: in-situ Mouse Apparatus 2015
An in vitro adult mouse muscle-nerve preparation for studying the firing properties of muscle afferents. Neuromuscular Neurodegenerative
809C: in-situ Mouse Apparatus 2014
C57BL/6 neuromuscular healthspan scoring system. Neuromuscular Neurodegenerative
604A | 604D | 604E: Data Acquisition Signal Interface 2013
C57BL/6 neuromuscular healthspan scoring system. Neuromuscular Neurodegenerative
605A: Dynamic Muscle Data Acquisition and Analysis System 2013
C57BL/6 neuromuscular healthspan scoring system. Neuromuscular Neurodegenerative
615A: Dynamic Muscle Control and Analysis Software 2013
Weakness of whole muscles in mice deficient in Cu, Zn superoxide dismutase is not explained by defects at the level of the contractile apparatus. Neuromuscular Neurodegenerative
802D: Permeabilized Fiber Apparatus – Microscope Mountable 2013
Neuromuscular Electrical Stimulation as a Method to Maximize the Beneficial Effects of Muscle Stem Cells Transplanted into Dystrophic Skeletal Muscle. Neuromuscular Dystrophy
809C: in-situ Mouse Apparatus 2013
Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases. Neuromuscular Neurodegenerative
806D: in-situ Rat Apparatus 2012
Orderly recruitment of motor units under optical control in vivo. Neuromuscular Neurodegenerative
300C: Dual-Mode Muscle Levers 2010
The differential effects of pathway-versus target-derived glial cell line-derived neurotrophic factor on peripheral nerve regeneration. Neuromuscular Neurodegenerative
605A: Dynamic Muscle Data Acquisition and Analysis System 2010
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