Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation. They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

Featured Publications

Encoding of location and intensity of noxious indentation into rat skin by spatial populations of cutaneous mechano-nociceptors.
Cross-bridge interaction kinetics in rat myocardium are accelerated by strong binding of myosin to the thin filament.
Strength training in older women: early and late changes in whole muscle and single cells.

Found 26 Results

Title	Research Area	Disease Model	System/Component	Year
Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9	Neuromuscular	Musculoskeletal	1200A: Isolated Muscle System for Mice	2023
Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis	Neuromuscular	Neurodegenerative	1200A: Isolated Muscle System for Mice	2023
Minocycline Treatment Reduces Mass and Force Output From Fast-Twitch Mouse Muscles and Inhibits Myosin Production in C2C12 Myotubes	Neuromuscular	Atrophy	615A: Dynamic Muscle Control and Analysis Software	2021
Paraspinal Muscle Contractile Function is Impaired in the ENT1-deficient Mouse Model of Progressive Spine Pathology	Neuromuscular	Neurodegenerative	901D: High-Speed Video Sarcomere Length	2021
Paraspinal Muscle Contractile Function is Impaired in the ENT1-deficient Mouse Model of Progressive Spine Pathology	Neuromuscular	Neurodegenerative	901D: High-Speed Video Sarcomere Length	2021
Optogenetic activation of muscle contraction in vivo	Neuromuscular	N/A		2021
Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy	Neuromuscular	Neurodegenerative	400B: Force Transducers	2020
Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease	Neuromuscular	Neurodegenerative	701C: Electrical Stimulator	2019
Follistatin-based ligand trap ACE-083 induces localized hypertrophy of skeletal muscle with functional improvement in models of neuromuscular disease	Neuromuscular	Neurodegenerative		2019
Extrinsic Primary Afferent Neurons Link Visceral Pain to Colon Motility Through a Spinal Reflex in Mice	Neuromuscular	Neurodegenerative	300C: Dual-Mode Muscle Levers	2019
Assessing Rat Forelimb and Hindlimb Motor Unit Connectivity as Objective and Robust Biomarkers of Spinal Motor Neuron Function	Neuromuscular	Neurodegenerative	1305A: 3-in-1 Whole Animal System for Rats	2019
Specific inhibition of myostatin activation is beneficial in mouse models of SMA therapy	Neuromuscular	Neurodegenerative		2019
Reversible temporally-specific inhibition of muscle using a light-activated chloride channel	Neuromuscular	Myopathy	300C: Dual-Mode Muscle Levers	2018
Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function.	Neuromuscular	Cancer	809C: in-situ Mouse Apparatus	2015
Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function.	Neuromuscular	Cancer	801C: Small Intact Muscle Apparatus – Microscope Mountable	2015
Measuring Neuromuscular Junction Functionality in the SOD1G93A Animal Model of Amyotrophic Lateral Sclerosis.	Neuromuscular	Neurodegenerative	701C: Electrical Stimulator	2015
Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function.	Neuromuscular	Cancer	1500A: Isolated Muscle System – Microscope Mountable	2015
An in vitro adult mouse muscle-nerve preparation for studying the firing properties of muscle afferents.	Neuromuscular	Neurodegenerative	809C: in-situ Mouse Apparatus	2014
Neuromuscular Electrical Stimulation as a Method to Maximize the Beneficial Effects of Muscle Stem Cells Transplanted into Dystrophic Skeletal Muscle.	Neuromuscular	Dystrophy	809C: in-situ Mouse Apparatus	2013
Weakness of whole muscles in mice deficient in Cu, Zn superoxide dismutase is not explained by defects at the level of the contractile apparatus.	Neuromuscular	Neurodegenerative	802D: Permeabilized Fiber Apparatus – Microscope Mountable	2013
C57BL/6 neuromuscular healthspan scoring system.	Neuromuscular	Neurodegenerative	615A: Dynamic Muscle Control and Analysis Software	2013
C57BL/6 neuromuscular healthspan scoring system.	Neuromuscular	Neurodegenerative	605A: Dynamic Muscle Data Acquisition and Analysis System	2013
C57BL/6 neuromuscular healthspan scoring system.	Neuromuscular	Neurodegenerative	604A \| 604D \| 604E: Data Acquisition Signal Interface	2013
Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases.	Neuromuscular	Neurodegenerative	806D: in-situ Rat Apparatus	2012
Orderly recruitment of motor units under optical control in vivo.	Neuromuscular	Neurodegenerative	300C: Dual-Mode Muscle Levers	2010
The differential effects of pathway-versus target-derived glial cell line-derived neurotrophic factor on peripheral nerve regeneration.	Neuromuscular	Neurodegenerative	605A: Dynamic Muscle Data Acquisition and Analysis System	2010

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