Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation.  They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

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Found 52 Results
Title Research Area Model Product Year
Ca2+ and force during dynamic contractions in mouse intact skeletal muscle fibers General Physiology N/A
1500A: Isolated Muscle System – Microscope Mountable 2024
Long-term musculoskeletal consequences of chemotherapy in pediatric mice General Physiology Cachexia
1300A: 3-in-1 Whole Animal System for Mice 2024
The carbon monoxide prodrug oCOm-21 increases Ca2+ sensitivity of the cardiac myofilament General Physiology N/A
1600A: Permeabilized Myocyte System – Microscope Mountable 2024
Myosin-binding protein C regulates the sarcomere lattice and stabilizes the OFF states of myosin heads General Physiology Cardiovascular
1600A: Permeabilized Myocyte System – Microscope Mountable 2024
Quantifying both viscoelasticity and surface tension: Why sharp tips overestimate cell stiffness General Physiology N/A
400A: Force Transducers 2024
Multiscale analysis of Klf10’s impact on the passive mechanical properties of murine skeletal muscle General Physiology Musculoskeletal
300C: Dual-Mode Muscle Levers, 1400A: Permeabilized Fiber System – Microscope Mountable, 802D: Permeabilized Fiber Apparatus – Microscope Mountable, 901D: High-Speed Video Sarcomere Length 2024
Endomysium determines active and passive force production in muscle fibers General Physiology N/A
802D: Permeabilized Fiber Apparatus – Microscope Mountable, 1400A: Permeabilized Fiber System – Microscope Mountable, 901D: High-Speed Video Sarcomere Length 2024
Fast myosin binding protein C knockout in skeletal muscle alters length-dependent activation and myofilament structure General Physiology N/A
400A: Force Transducers, 315D/322D: High-Speed Length Controllers, 600A: Real-Time Muscle Data Acquisition and Analysis System 2024
Number of denatured rigor cross-bridges determines the intracellular volume shrinkage in porcine muscle fibre under PSE-inducing condition General Physiology N/A
1400A: Permeabilized Fiber System – Microscope Mountable, 901D: High-Speed Video Sarcomere Length 2024
Skeletal Muscle Heat Shock Protein Content and the Repeated Bout Effect General Physiology N/A
806D: in-situ Rat Apparatus, 604A | 604D | 604E: Data Acquisition Signal Interface, 615A: Dynamic Muscle Control and Analysis Software, 1305A: 3-in-1 Whole Animal System for Rats 2024
Exploring the muscle architecture effect on the mechanical behaviour of mouse rotator cuff muscles General Physiology N/A
1200A: Isolated Muscle System for Rodents, 800C: in-vitro Muscle Apparatus 2024
Impact of lengthening velocity on the generation of eccentric force by slow-twitch muscle fibers in long stretches General Physiology N/A
600A: Real-Time Muscle Data Acquisition and Analysis System, 400A: Force Transducers, 315D/322D: High-Speed Length Controllers, 604A | 604D | 604E: Data Acquisition Signal Interface, 1400A: Permeabilized Fiber System – Microscope Mountable, 901D: High-Speed Video Sarcomere Length 2024
The impacts of muscle-specific force-velocity properties on predictions of mouse muscle function during locomotion General Physiology N/A
701C: Electrical Stimulator, 615A: Dynamic Muscle Control and Analysis Software, 800A/805A: in-vitro Muscle Apparatus, 300C: Dual-Mode Muscle Levers 2024
The road not taken: Evolution of tetrodotoxin resistance in the Sierra garter snake (Thamnophis couchii) by a path less traveled General Physiology N/A
800A/805A: in-vitro Muscle Apparatus 2022
Constitutive assembly of Ca2+ entry units in soleus muscle from calsequestrin knockout mice General Physiology Musculoskeletal
1200A: Isolated Muscle System for Rodents 2022
Ultrastructural and kinetic evidence support that thick filaments slide through the Z-disc General Physiology N/A
1400A: Permeabilized Fiber System – Microscope Mountable 2022
Comparing contractile properties within an integrated group of muscles: The abdominal wall General Physiology N/A
400A: Force Transducers, 315D/322D: High-Speed Length Controllers, 802D: Permeabilized Fiber Apparatus – Microscope Mountable, 600A: Real-Time Muscle Data Acquisition and Analysis System, 1400A: Permeabilized Fiber System – Microscope Mountable, 901D: High-Speed Video Sarcomere Length 2022
One-to-one innervation of vocal muscles allows precise control of birdsong General Physiology N/A
2021
A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues General Physiology Myopathy
1600A: Permeabilized Myocyte System – Microscope Mountable 2020
In vitro virtual reality: an anatomically explicit musculoskeletal simulation powered by in vitro muscle using closed-loop tissue–software interaction General Physiology N/A
300C: Dual-Mode Muscle Levers 2020
On a coupled electro-chemomechanical model of gastric smooth muscle contraction General Physiology N/A
800A/805A: in-vitro Muscle Apparatus 2020
Pharmacological Mitigation of Fibrosis in a Porcine Model of Volumetric Muscle Loss Injury General Physiology Volumetric Muscle Loss
890A: in-situ Large Animal Apparatus 2020
Cardiac myosin binding protein-C phosphorylation regulates the super-relaxed state of myosin. General Physiology Myopathy
600A: Real-Time Muscle Data Acquisition and Analysis System 2019
Cardiac myosin binding protein-C phosphorylation regulates the super-relaxed state of myosin. General Physiology Myopathy
650A: Real-Time Muscle Data Acquisition and Analysis Software 2019
Extracellular matrix stiffness regulates human airway smooth muscle contraction by altering the cell-cell coupling General Physiology Asthma
300C: Dual-Mode Muscle Levers 2019
Passive force and viscoelastic properties of single fibers in human aging muscles General Physiology Aging
2019
Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy General Physiology Myopathy
1500A: Isolated Muscle System – Microscope Mountable 2018
Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy General Physiology Myopathy
650A: Real-Time Muscle Data Acquisition and Analysis Software 2018
Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy General Physiology Myopathy
901D: High-Speed Video Sarcomere Length 2018
The active force-length relationship is invisible during extensive eccentric contractions in skinned skeletal muscle fibres. General Physiology N/A
901D: High-Speed Video Sarcomere Length 2017
The giant protein titin regulates the length of the striated muscle thick filament. General Physiology Myopathy
901D: High-Speed Video Sarcomere Length 2017
Influence of residual force enhancement and elongation of attached cross-bridges on stretch-shortening cycle in skinned muscle fibers General Physiology N/A
802D: Permeabilized Fiber Apparatus – Microscope Mountable 2017
Influence of residual force enhancement and elongation of attached cross-bridges on stretch-shortening cycle in skinned muscle fibers General Physiology N/A
2017
Computing Average Passive Forces in Sarcomeres in Length-Ramp Simulations . General Physiology Myopathy
1700A: Myofibril System – Microscope Mountable 2016
The increase in non-cross-bridge forces after stretch of activated striated muscle is related to titin isoforms. General Physiology Myopathy
1700A: Myofibril System – Microscope Mountable 2016
Reduced passive force in skeletal muscles lacking protein arginylation. General Physiology Myopathy
1700A: Myofibril System – Microscope Mountable 2016
Decreased force enhancement in skeletal muscle sarcomeres with a deletion in titin. General Physiology Myopathy
1700A: Myofibril System – Microscope Mountable 2016
Myosin filament sliding through the Z-disc relates striated muscle fibre structure to function General Physiology Myopathy
1400A: Permeabilized Fiber System – Microscope Mountable 2016
Relaxant effect of superimposed length oscillation on sensitized airway smooth muscle. General Physiology Asthma
800A/805A: in-vitro Muscle Apparatus 2015
Muscle Unloading Induced Sex Specific Neurophysiological and Myofiber Profile Adaptations. General Physiology Atrophy
807B: in-situ Large Rodent/Small Animal Apparatus 2015
Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle. General Physiology Myopathy
950A: Calcium Fluorescence System 2015
Effects of aging on the lateral transmission of force in rat skeletal muscle. General Physiology Aging
1205A: Isolated Muscle System for Rats 2014
Method and apparatus for measuring cantilever deflection in constrained spaces. General Physiology N/A
1700A: Myofibril System – Microscope Mountable 2014
Developmental changes in diaphragm muscle function in the preterm and postnatal lamb. General Physiology Development
1205A: Isolated Muscle System for Rats 2013
Calcium sensitivity and myofilament lattice structure in titin N2B KO mice. General Physiology Myopathy
1400A: Permeabilized Fiber System – Microscope Mountable 2013
Low Po2 conditions induce reactive oxygen species formation during contractions in single skeletal muscle fibers. General Physiology Aging
1500A: Isolated Muscle System – Microscope Mountable 2013
Calcium sensitivity and myofilament lattice structure in titin N2B KO mice. General Physiology Myopathy
802D: Permeabilized Fiber Apparatus – Microscope Mountable 2013
Optical detection system for probing cantilever deflections parallel to a sample surface. General Physiology N/A
1700A: Myofibril System – Microscope Mountable 2011
Analysing force-pCa curves. General Physiology N/A
315D/322D: High-Speed Length Controllers 2010
Altered contractility of skeletal muscle in mice deficient in titin’s M-band region. General Physiology Myopathy
1200A: Isolated Muscle System for Rodents 2009
ltered contractility of skeletal muscle in mice deficient in titin’s M-band region. General Physiology Myopathy
300C: Dual-Mode Muscle Levers 2009
Effects of a preferential myosin loss on Ca2+ activation of force generation in single human skeletal muscle fibres. General Physiology Myopathy
1400A: Permeabilized Fiber System – Microscope Mountable 2008
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