Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation.  They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

Featured Publications

Found 31 Results
Title Research Area Disease Model System/Component Year
Pharmacological Mitigation of Fibrosis in a Porcine Model of Volumetric Muscle Loss Injury General Physiology Volumetric Muscle Loss
 890A: in-situ Large Animal Apparatus 2020
A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues General Physiology Myopathy
 1600A: Permeabilized Myocyte System – Microscope Mountable 2020
In vitro virtual reality: an anatomically explicit musculoskeletal simulation powered by in vitro muscle using closed-loop tissue–software interaction General Physiology N/A
 300C: Dual-Mode Muscle Levers 2020
Extracellular matrix stiffness regulates human airway smooth muscle contraction by altering the cell-cell coupling General Physiology Asthma
 300C: Dual-Mode Muscle Levers 2019
Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy General Physiology Myopathy
 650A: Real-Time Muscle Data Acquisition and Analysis Software 2018
Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy General Physiology Myopathy
 901D: High-Speed Video Sarcomere Length 2018
Myosin filament sliding through the Z-disc relates striated muscle fibre structure to function General Physiology Myopathy
 1400A: Permeabilized Fiber System – Microscope Mountable 2016
Influence of residual force enhancement and elongation of attached cross-bridges on stretch-shortening cycle in skinned muscle fibers General Physiology N/A
 802D: Permeabilized Fiber Apparatus – Microscope Mountable 2017
Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy General Physiology Myopathy
 1500A: Isolated Muscle System – Microscope Mountable 2018
Cardiac myosin binding protein-C phosphorylation regulates the super-relaxed state of myosin. General Physiology Myopathy
 600A: Real-Time Muscle Data Acquisition and Analysis System 2019
Cardiac myosin binding protein-C phosphorylation regulates the super-relaxed state of myosin. General Physiology Myopathy
 650A: Real-Time Muscle Data Acquisition and Analysis Software 2019
Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle. General Physiology Myopathy
 950A: Calcium Fluorescence System 2015
Computing Average Passive Forces in Sarcomeres in Length-Ramp Simulations . General Physiology Myopathy
 1700A: Myofibril System – Microscope Mountable 2016
The increase in non-cross-bridge forces after stretch of activated striated muscle is related to titin isoforms. General Physiology Myopathy
 1700A: Myofibril System – Microscope Mountable 2016
Reduced passive force in skeletal muscles lacking protein arginylation. General Physiology Myopathy
 1700A: Myofibril System – Microscope Mountable 2016
Decreased force enhancement in skeletal muscle sarcomeres with a deletion in titin. General Physiology Myopathy
 1700A: Myofibril System – Microscope Mountable 2016
The active force-length relationship is invisible during extensive eccentric contractions in skinned skeletal muscle fibres. General Physiology N/A
 901D: High-Speed Video Sarcomere Length 2017
The giant protein titin regulates the length of the striated muscle thick filament. General Physiology Myopathy
 901D: High-Speed Video Sarcomere Length 2017
Relaxant effect of superimposed length oscillation on sensitized airway smooth muscle. General Physiology Asthma
 800A/805A: in-vitro Muscle Apparatus 2015
Muscle Unloading Induced Sex Specific Neurophysiological and Myofiber Profile Adaptations. General Physiology Atrophy
 807B: in-situ Large Rodent/Small Animal Apparatus 2015
Method and apparatus for measuring cantilever deflection in constrained spaces. General Physiology N/A
 1700A: Myofibril System – Microscope Mountable 2014
Calcium sensitivity and myofilament lattice structure in titin N2B KO mice. General Physiology Myopathy
 802D: Permeabilized Fiber Apparatus – Microscope Mountable 2013
Effects of aging on the lateral transmission of force in rat skeletal muscle. General Physiology Aging
 1205A: Isolated Muscle System for Rats 2014
Developmental changes in diaphragm muscle function in the preterm and postnatal lamb. General Physiology Development
 1205A: Isolated Muscle System for Rats 2013
Calcium sensitivity and myofilament lattice structure in titin N2B KO mice. General Physiology Myopathy
 1400A: Permeabilized Fiber System – Microscope Mountable 2013
Low Po2 conditions induce reactive oxygen species formation during contractions in single skeletal muscle fibers. General Physiology Aging
 1500A: Isolated Muscle System – Microscope Mountable 2013
Optical detection system for probing cantilever deflections parallel to a sample surface. General Physiology N/A
 1700A: Myofibril System – Microscope Mountable 2011
ltered contractility of skeletal muscle in mice deficient in titin’s M-band region. General Physiology Myopathy
 300C: Dual-Mode Muscle Levers 2009
Analysing force-pCa curves. General Physiology N/A
 315D/322D: High-Speed Length Controllers 2010
Effects of a preferential myosin loss on Ca2+ activation of force generation in single human skeletal muscle fibres. General Physiology Myopathy
 1400A: Permeabilized Fiber System – Microscope Mountable 2008
Altered contractility of skeletal muscle in mice deficient in titin’s M-band region. General Physiology Myopathy
 1200A: Isolated Muscle System for Mice 2009
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