Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation.  They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

Featured Publications

Found 19 Results
Title Research Area Disease Model System/Component Year
Microdystrophin Gene Addition Significantly Improves Muscle Functionality and Diaphragm Muscle Histopathology in a Fibrotic Mouse Model of Duchenne Muscular Dystrophy Muscle Pathology & Wasting DMD
 1300A: 3-in-1 Whole Animal System for Mice 2023
Anti-RANKL Therapy Prevents Glucocorticoid-Induced Bone Loss and Promotes Muscle Function in a Mouse Model of Duchenne Muscular Dystrophy Molecular Biology and Pharmacology DMD
 1200A: Isolated Muscle System for Mice 2023
Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy Molecular Biology and Pharmacology DMD
 1400A: Permeabilized Fiber System – Microscope Mountable 2023
Efficient precise in vivo base editing in adultdystrophic mice Muscle Pathology & Wasting DMD
 2021
Targeted genome editing in vivo corrects a Dmd duplication restoring wild-type dystrophin expression Muscle Pathology & Wasting DMD
 1300A: 3-in-1 Whole Animal System for Mice 2021
Dose-Escalation Study of Systemically Delivered rAAVrh74.MHCK7.micro-dystrophin in the mdx Mouse Model of Duchenne Muscular Dystrophy Muscle Pathology & Wasting DMD
 2021
Efficient precise in vivo base editing in adultdystrophic mice Muscle Pathology & Wasting DMD
 2021
Targeted genome editing in vivo corrects a Dmd duplication restoring wild-type dystrophin expression Muscle Pathology & Wasting DMD
 2021
A novel ex vivo protocol to mimic human walking gait: implications for Duchenne muscular dystrophy Muscle Pathology & Wasting DMD
 1300A: 3-in-1 Whole Animal System for Mice 2020
Contractile efficiency of dystrophic mdx mouse muscle: in vivo and ex vivo assessment of adaptation to exercise of functional end points Muscle Pathology & Wasting DMD
 615A: Dynamic Muscle Control and Analysis Software 2017
Whole body periodic acceleration is an effective therapy to ameliorate muscular dystrophy in mdx mice. Muscle Pathology & Wasting DMD
 615A: Dynamic Muscle Control and Analysis Software 2014
Effects of prednisolone on the dystrophin-associated proteins in the blood-brain barrier and skeletal muscle of dystrophic mdx mice. Muscle Pathology & Wasting DMD
 615A: Dynamic Muscle Control and Analysis Software 2013
Physiological characterization of muscle strength with variable levels of dystrophin restoration in mdx mice following local antisense therapy. Muscle Pathology & Wasting DMD
 701C: Electrical Stimulator 2011
The passive mechanical properties of the extensor digitorum longus muscle are compromised in 2- to 20-mo-old mdx mice. Muscle Pathology & Wasting DMD
 615A: Dynamic Muscle Control and Analysis Software 2011
Physiological characterization of muscle strength with variable levels of dystrophin restoration in mdx mice following local antisense therapy. Muscle Pathology & Wasting DMD
 615A: Dynamic Muscle Control and Analysis Software 2011
Combination of myostatin pathway interference and dystrophin rescue enhances tetanic and specific force in dystrophic mdx mice. Muscle Pathology & Wasting DMD
 300C: Dual-Mode Muscle Levers 2010
Single muscle fiber contractile properties in adults with muscular dystrophy treated with MYO‐029. Muscle Pathology & Wasting DMD
 400B: Force Transducers 2009
Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury. Muscle Pathology & Wasting DMD
 605A: Dynamic Muscle Data Acquisition and Analysis System 2005
Poloxamer 188 reduces the contraction-induced force decline in lumbrical muscles from mdx mice. Muscle Pathology & Wasting DMD
 400B: Force Transducers 2008
Subscribe to Aurora Scientific to receive technology, applications and event news