Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation.  They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

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Found 20 Results
Title Research Area Model Product Year
Running improves muscle mass by activating autophagic flux and inhibiting ubiquitination degradation in mdx mice Muscle Pathology & Wasting DMD
1300A: 3-in-1 Whole Animal System for Mice 2024
Microdystrophin Gene Addition Significantly Improves Muscle Functionality and Diaphragm Muscle Histopathology in a Fibrotic Mouse Model of Duchenne Muscular Dystrophy Muscle Pathology & Wasting DMD
1300A: 3-in-1 Whole Animal System for Mice 2023
Anti-RANKL Therapy Prevents Glucocorticoid-Induced Bone Loss and Promotes Muscle Function in a Mouse Model of Duchenne Muscular Dystrophy Molecular Biology and Pharmacology DMD
1200A: Isolated Muscle System for Rodents 2023
Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy Molecular Biology and Pharmacology DMD
1400A: Permeabilized Fiber System – Microscope Mountable 2023
Targeted genome editing in vivo corrects a Dmd duplication restoring wild-type dystrophin expression Muscle Pathology & Wasting DMD
1300A: 3-in-1 Whole Animal System for Mice 2021
Efficient precise in vivo base editing in adultdystrophic mice Muscle Pathology & Wasting DMD
1300A: 3-in-1 Whole Animal System for Mice 2021
Targeted genome editing in vivo corrects a Dmd duplication restoring wild-type dystrophin expression Muscle Pathology & Wasting DMD
1300A: 3-in-1 Whole Animal System for Mice 2021
Efficient precise in vivo base editing in adultdystrophic mice Muscle Pathology & Wasting DMD
1300A: 3-in-1 Whole Animal System for Mice 2021
Dose-Escalation Study of Systemically Delivered rAAVrh74.MHCK7.micro-dystrophin in the mdx Mouse Model of Duchenne Muscular Dystrophy Muscle Pathology & Wasting DMD
1305A: 3-in-1 Whole Animal System for Rats 2021
A novel ex vivo protocol to mimic human walking gait: implications for Duchenne muscular dystrophy Muscle Pathology & Wasting DMD
1300A: 3-in-1 Whole Animal System for Mice 2020
Contractile efficiency of dystrophic mdx mouse muscle: in vivo and ex vivo assessment of adaptation to exercise of functional end points Muscle Pathology & Wasting DMD
615A: Dynamic Muscle Control and Analysis Software 2017
Whole body periodic acceleration is an effective therapy to ameliorate muscular dystrophy in mdx mice. Muscle Pathology & Wasting DMD
615A: Dynamic Muscle Control and Analysis Software 2014
Effects of prednisolone on the dystrophin-associated proteins in the blood-brain barrier and skeletal muscle of dystrophic mdx mice. Muscle Pathology & Wasting DMD
615A: Dynamic Muscle Control and Analysis Software 2013
Physiological characterization of muscle strength with variable levels of dystrophin restoration in mdx mice following local antisense therapy. Muscle Pathology & Wasting DMD
615A: Dynamic Muscle Control and Analysis Software 2011
The passive mechanical properties of the extensor digitorum longus muscle are compromised in 2- to 20-mo-old mdx mice. Muscle Pathology & Wasting DMD
615A: Dynamic Muscle Control and Analysis Software 2011
Physiological characterization of muscle strength with variable levels of dystrophin restoration in mdx mice following local antisense therapy. Muscle Pathology & Wasting DMD
701C: Electrical Stimulator 2011
Combination of myostatin pathway interference and dystrophin rescue enhances tetanic and specific force in dystrophic mdx mice. Muscle Pathology & Wasting DMD
300C: Dual-Mode Muscle Levers 2010
Single muscle fiber contractile properties in adults with muscular dystrophy treated with MYO‐029. Muscle Pathology & Wasting DMD
400B: Force Transducers 2009
Poloxamer 188 reduces the contraction-induced force decline in lumbrical muscles from mdx mice. Muscle Pathology & Wasting DMD
400B: Force Transducers 2008
Adeno-associated virus-mediated microdystrophin expression protects young mdx muscle from contraction-induced injury. Muscle Pathology & Wasting DMD
605A: Dynamic Muscle Data Acquisition and Analysis System 2005
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