Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation.  They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

Featured Publications

Found 27 Results
Title Research Area Disease Model System/Component Year
RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes Molecular Biology and Pharmacology Atrophy
315D/322D: High-Speed Length Controllers 2018
Cigarette smoke directly impairs skeletal muscle function through capillary regression and altered myofibre calcium kinetics in mice Molecular Biology and Pharmacology Cardiovascular
1500A: Isolated Muscle System – Microscope Mountable 2018
Myosin Head Configurations in Resting and Contracting Murine Skeletal Muscle Molecular Biology and Pharmacology Myopathy
300C: Dual-Mode Muscle Levers 2018
Effect of levosimendan on the contractility of muscle fibers from nemaline myopathy patients with mutations in the nebulin gene. Molecular Biology and Pharmacology Myopathy
825A: Thermocouple Meter / TEC Controller 2015
MgADP activation contributes to force enhancement during fast stretch of isolated skeletal myofibrils. Molecular Biology and Pharmacology N/A
1700A: Myofibril System – Microscope Mountable 2015
Osteoprotegerin Protects against Muscular Dystrophy. Molecular Biology and Pharmacology Dystrophy
615A: Dynamic Muscle Control and Analysis Software 2015
Inhibition of activin A ameliorates skeletal muscle injury and rescues contractile properties by inducing efficient remodeling in female mice. Molecular Biology and Pharmacology Injury
807B: in-situ Large Rodent/Small Animal Apparatus 2014
Follistatin: a novel therapeutic for the improvement of muscle regeneration. Molecular Biology and Pharmacology Atrophy
807B: in-situ Large Rodent/Small Animal Apparatus 2014
Muscle histopathology in nebulin-related nemaline myopathy: ultrastrastructural findings correlated to disease severity and genotype. Molecular Biology and Pharmacology Myopathy
825A: Thermocouple Meter / TEC Controller 2014
Interleukin-1 Receptor Antagonist Protects against Lipopolysaccharide Induced Diaphragm Weakness in Preterm Lambs. Molecular Biology and Pharmacology Development
1205A: Isolated Muscle System for Rats 2015
Arginylation of Myosin Heavy Chain Regulates Skeletal Muscle Strength. Molecular Biology and Pharmacology N/A
1700A: Myofibril System – Microscope Mountable 2014
Nitrosative modifications of the Ca2+ release complex and actin underlie arthritis-induced muscle weakness. Molecular Biology and Pharmacology Sarcopenia
1700A: Myofibril System – Microscope Mountable 2014
Systems-based discovery of tomatidine as a natural small molecule inhibitor of skeletal muscle atrophy. Molecular Biology and Pharmacology Atrophy
800A/805A: in-vitro Muscle Apparatus 2014
A gain-of-function mutation in the M-domain of cardiac myosin-binding protein-C increases binding to actin Molecular Biology and Pharmacology Cardiovascular
802D: Permeabilized Fiber Apparatus – Microscope Mountable 2013
Whey proteins are more efficient than casein in the recovery of muscle functional properties following a casting induced muscle atrophy. Molecular Biology and Pharmacology Atrophy
806D: in-situ Rat Apparatus 2013
The timing of administration of a clinically relevant dose of losartan influences the healing process after contusion induced muscle injury. Molecular Biology and Pharmacology Injury
809C: in-situ Mouse Apparatus 2013
Effect of maternal steroid on developing diaphragm integrity. Molecular Biology and Pharmacology Development
1205A: Isolated Muscle System for Rats 2014
Contractility of myofibrils from the heart and diaphragm muscles measured with atomic force cantilevers: Effects of heart-specific deletion of arginyl-tRNA-protein transferase. Molecular Biology and Pharmacology Cardiovascular
1700A: Myofibril System – Microscope Mountable 2013
Mitochondria-targeted antiaging gene therapy with adeno-associated viral vectors. Molecular Biology and Pharmacology Aging
604A | 604D | 604E: Data Acquisition Signal Interface 2013
Mitochondria-targeted antiaging gene therapy with adeno-associated viral vectors. Molecular Biology and Pharmacology Aging
605A: Dynamic Muscle Data Acquisition and Analysis System 2013
Genomic and proteomic profiling reveals reduced mitochondrial function and disruption of the neuromuscular junction driving rat sarcopenia. Molecular Biology and Pharmacology Sarcopenia
1305A: 3-in-1 Whole Animal System for Rats 2013
Androgen replacement therapy improves function in male rat muscles independently of hypertrophy and activation of the Akt/mTOR pathway. Molecular Biology and Pharmacology Aging
300C: Dual-Mode Muscle Levers 2009
Striated Muscles: From Molecules to Cells. Molecular Biology and Pharmacology N/A
1700A: Myofibril System – Microscope Mountable 2010
Dihydrotestosterone activates the MAPK pathway and modulates maximum isometric force through the EGF receptor in isolated intact mouse skeletal muscle fibres. Molecular Biology and Pharmacology N/A
825A: Thermocouple Meter / TEC Controller 2010
Clenbuterol and formoterol decrease force production in isolated intact mouse skeletal muscle fiber bundles through a beta2-adrenoceptor-independent mechanism. Molecular Biology and Pharmacology N/A
825A: Thermocouple Meter / TEC Controller 2010
Effects of buthionine sulfoximine treatment on diaphragm contractility and SR Ca2+ pump function in rats. Molecular Biology and Pharmacology N/A
605A: Dynamic Muscle Data Acquisition and Analysis System 2007
904-Plat Critical Sarcomere Length Extension and Phase Transition Of Force During Lengthening Of Skeletal Muscle Myofibrils. Molecular Biology and Pharmacology N/A
1700A: Myofibril System – Microscope Mountable 2008
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