Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation.  They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

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Found 35 Results
Title Research Area Model Product Year
Anti-RANKL Therapy Prevents Glucocorticoid-Induced Bone Loss and Promotes Muscle Function in a Mouse Model of Duchenne Muscular Dystrophy Molecular Biology and Pharmacology DMD
1200A: Isolated Muscle System for Rodents 2023
Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy Molecular Biology and Pharmacology DMD
1400A: Permeabilized Fiber System – Microscope Mountable 2023
Skeletal muscle delimited myopathy and verapamil toxicity in SUR2 mutant mouse models of AIMS Molecular Biology and Pharmacology Myopathy
1300A: 3-in-1 Whole Animal System for Mice 2023
microRNA‐29a Regulates ADAM12 Through Direct Interaction With ADAM12 mRNA and Modulates Postischemic Perfusion Recovery Molecular Biology and Pharmacology Ischmia/Reperfusion
1300A: 3-in-1 Whole Animal System for Mice 2022
Novel γ-sarcoglycan interactors in murine muscle membranes Molecular Biology and Pharmacology Dystrophy
800A/805A: in-vitro Muscle Apparatus 2022
The CARM1 transcriptome and arginine methylproteome mediate skeletal muscle integrative biology Molecular Biology and Pharmacology Development
615A: Dynamic Muscle Control and Analysis Software 2022
BAG3 Attenuates Ischemia-Induced Skeletal Muscle Necroptosis in Diabetic Experimental Peripheral Artery Disease Molecular Biology and Pharmacology Diabetes
1300A: 3-in-1 Whole Animal System for Mice 2022
Cigarette smoke directly impairs skeletal muscle function through capillary regression and altered myofibre calcium kinetics in mice Molecular Biology and Pharmacology Cardiovascular
1500A: Isolated Muscle System – Microscope Mountable 2018
Myosin Head Configurations in Resting and Contracting Murine Skeletal Muscle Molecular Biology and Pharmacology Myopathy
300C: Dual-Mode Muscle Levers 2018
RNA helicase, DDX27 regulates skeletal muscle growth and regeneration by modulation of translational processes Molecular Biology and Pharmacology Atrophy
315D/322D: High-Speed Length Controllers 2018
SIRT1 regulates nuclear number and domain size in skeletal muscle fibers Molecular Biology and Pharmacology N/A
2018
Interleukin-1 Receptor Antagonist Protects against Lipopolysaccharide Induced Diaphragm Weakness in Preterm Lambs. Molecular Biology and Pharmacology Development
1205A: Isolated Muscle System for Rats 2015
MgADP activation contributes to force enhancement during fast stretch of isolated skeletal myofibrils. Molecular Biology and Pharmacology N/A
1700A: Myofibril System – Microscope Mountable 2015
Osteoprotegerin Protects against Muscular Dystrophy. Molecular Biology and Pharmacology Dystrophy
615A: Dynamic Muscle Control and Analysis Software 2015
Effect of levosimendan on the contractility of muscle fibers from nemaline myopathy patients with mutations in the nebulin gene. Molecular Biology and Pharmacology Myopathy
825A: Thermocouple Meter / TEC Controller 2015
Effect of maternal steroid on developing diaphragm integrity. Molecular Biology and Pharmacology Development
1205A: Isolated Muscle System for Rats 2014
Arginylation of Myosin Heavy Chain Regulates Skeletal Muscle Strength. Molecular Biology and Pharmacology N/A
1700A: Myofibril System – Microscope Mountable 2014
Nitrosative modifications of the Ca2+ release complex and actin underlie arthritis-induced muscle weakness. Molecular Biology and Pharmacology Sarcopenia
1700A: Myofibril System – Microscope Mountable 2014
Systems-based discovery of tomatidine as a natural small molecule inhibitor of skeletal muscle atrophy. Molecular Biology and Pharmacology Atrophy
800A/805A: in-vitro Muscle Apparatus 2014
Inhibition of activin A ameliorates skeletal muscle injury and rescues contractile properties by inducing efficient remodeling in female mice. Molecular Biology and Pharmacology Injury
807B: in-situ Large Rodent/Small Animal Apparatus 2014
Follistatin: a novel therapeutic for the improvement of muscle regeneration. Molecular Biology and Pharmacology Atrophy
807B: in-situ Large Rodent/Small Animal Apparatus 2014
Muscle histopathology in nebulin-related nemaline myopathy: ultrastrastructural findings correlated to disease severity and genotype. Molecular Biology and Pharmacology Myopathy
825A: Thermocouple Meter / TEC Controller 2014
Genomic and proteomic profiling reveals reduced mitochondrial function and disruption of the neuromuscular junction driving rat sarcopenia. Molecular Biology and Pharmacology Sarcopenia
1305A: 3-in-1 Whole Animal System for Rats 2013
Contractility of myofibrils from the heart and diaphragm muscles measured with atomic force cantilevers: Effects of heart-specific deletion of arginyl-tRNA-protein transferase. Molecular Biology and Pharmacology Cardiovascular
1700A: Myofibril System – Microscope Mountable 2013
Mitochondria-targeted antiaging gene therapy with adeno-associated viral vectors. Molecular Biology and Pharmacology Aging
604A | 604D | 604E: Data Acquisition Signal Interface 2013
Mitochondria-targeted antiaging gene therapy with adeno-associated viral vectors. Molecular Biology and Pharmacology Aging
605A: Dynamic Muscle Data Acquisition and Analysis System 2013
A gain-of-function mutation in the M-domain of cardiac myosin-binding protein-C increases binding to actin Molecular Biology and Pharmacology Cardiovascular
802D: Permeabilized Fiber Apparatus – Microscope Mountable 2013
Whey proteins are more efficient than casein in the recovery of muscle functional properties following a casting induced muscle atrophy. Molecular Biology and Pharmacology Atrophy
806D: in-situ Rat Apparatus 2013
The timing of administration of a clinically relevant dose of losartan influences the healing process after contusion induced muscle injury. Molecular Biology and Pharmacology Injury
809C: in-situ Mouse Apparatus 2013
Striated Muscles: From Molecules to Cells. Molecular Biology and Pharmacology N/A
1700A: Myofibril System – Microscope Mountable 2010
Dihydrotestosterone activates the MAPK pathway and modulates maximum isometric force through the EGF receptor in isolated intact mouse skeletal muscle fibres. Molecular Biology and Pharmacology N/A
825A: Thermocouple Meter / TEC Controller 2010
Clenbuterol and formoterol decrease force production in isolated intact mouse skeletal muscle fiber bundles through a beta2-adrenoceptor-independent mechanism. Molecular Biology and Pharmacology N/A
825A: Thermocouple Meter / TEC Controller 2010
Androgen replacement therapy improves function in male rat muscles independently of hypertrophy and activation of the Akt/mTOR pathway. Molecular Biology and Pharmacology Aging
300C: Dual-Mode Muscle Levers 2009
904-Plat Critical Sarcomere Length Extension and Phase Transition Of Force During Lengthening Of Skeletal Muscle Myofibrils. Molecular Biology and Pharmacology N/A
1700A: Myofibril System – Microscope Mountable 2008
Effects of buthionine sulfoximine treatment on diaphragm contractility and SR Ca2+ pump function in rats. Molecular Biology and Pharmacology N/A
605A: Dynamic Muscle Data Acquisition and Analysis System 2007
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