MYTHO is a novel regulator of skeletal muscle autophagy and integrity
The study identifies a novel FoxO-dependent gene called Mytho (Macroautophagy and YouTH Optimizer) as a regulator of autophagy and skeletal
Blocking muscle wasting via deletion of the muscle-specific E3 ligase MuRF1 impedes pancreatic tumor growth
Cancer-induced muscle wasting significantly impacts quality of life, hinders cancer treatments, and predicts early mortality. This study explores the role
Microdystrophin Gene Addition Significantly Improves Muscle Functionality and Diaphragm Muscle Histopathology in a Fibrotic Mouse Model of Duchenne Muscular Dystrophy
This study investigates the effectiveness of adeno-associated viral (AAV) vector-mediated microdystrophin gene addition therapy in a fibrotic mouse model of
In Vivo Measurement of Hindlimb Dorsiflexor Isometric Torque from Pig
The present protocol describes concise experimental details on the evaluation and interpretation of in vivo torque data obtained via electrical stimulation of the common peroneal nerve in ...
Out of This World Research at Brock University: Space Flight’s Impact on Female Mice Reproductive Health
NASA's SpaceX CRS-29 launched on November 9th carrying the Rodent Research-20 (RR-20) payload, the contents of which will be studied by Brock University's Dr. Val Fajardo and his team using Aurora ...
Cancer Cachexia-Induced Muscle Atrophy
Cancer cachexia is a muscle wasting syndrome that is associated with certain cancers, but most commonly with advanced malignancies. This syndrome arises as a result of tumor-induced metabolic ...
Recent Therapeutic Advances in Duchenne Muscular Dystrophy (DMD) Models
The following publication review showcases recent studies focused on therapeutic advances in Duchenne Muscular Dystrophy (DMD) that use Aurora Scientific ...
Exercise Science
Aurora Scientific equipment has played important roles in helping researchers understand muscle physiology under a variety of conditions in animal models as highlighted in this publication ...
Designing an in-vivo study in DMC LabBook
This blog will provide a walkthrough of how to design a study in our Dynamic Muscle Control (DMC) LabBook software, specifically for 1300A 3-in-1 Whole Animal System in-vivo experiments.