E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction.

• Author(s): de Lange, Willem J. et al.
• Year: 2013
• DOI: 10.1085/jgp.201311018
• PMID: 23980194
• Related Product: 801C: Small Intact Muscle Apparatus – Microscope Mountable
• Research Areas: Cardiology
• Disease Models: Myopathy