Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation.  They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

Found 19 Results
Title Research Area Disease Model System/Component Year
Blocking muscle wasting via deletion of the muscle-specific E3 ligase MuRF1 impedes pancreatic tumor growth Muscle Pathology & Wasting Cancer
1200A: Isolated Muscle System for Mice 2023
Anti-RANKL Therapy Prevents Glucocorticoid-Induced Bone Loss and Promotes Muscle Function in a Mouse Model of Duchenne Muscular Dystrophy Molecular Biology and Pharmacology DMD
1200A: Isolated Muscle System for Mice 2023
Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9 Neuromuscular Musculoskeletal
1200A: Isolated Muscle System for Mice 2023
Constitutive assembly of Ca2+ entry units in soleus muscle from calsequestrin knockout mice General Physiology Musculoskeletal
1200A: Isolated Muscle System for Mice 2022
Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis Neuromuscular Neurodegenerative
1200A: Isolated Muscle System for Mice 2023
High-Fat Diet Impairs Muscle Function and Increases the Risk of Environmental Heatstroke in Mice Exercise & Metabolism N/A
1200A: Isolated Muscle System for Mice 2022
Store-Operated Ca2+ Entry in Skeletal Muscle Contributes to the Increase in Body Temperature during Exertional Stress Exercise & Metabolism N/A
1200A: Isolated Muscle System for Mice 2022
Inhibition of inflammatory CCR2 signaling promotes aged muscle regeneration and strength recovery after injury Muscle Pathology & Wasting Aging
1200A: Isolated Muscle System for Mice 2020
Dietary nitrate supplementation increases diaphragm peak power in old mice Muscle Pathology & Wasting Aging
1200A: Isolated Muscle System for Mice 2020
Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weakness Muscle Pathology & Wasting Atrophy
1200A: Isolated Muscle System for Mice 2019
Chemotherapy-induced loss of bone and muscle mass in a mouse model of breast cancer bone metastases and cachexia Muscle Pathology & Wasting Cachexia
1200A: Isolated Muscle System for Mice 2019
Oxidative stress-induced dysregulation of excitation–contraction coupling contributes to muscle weakness Muscle Pathology & Wasting Sarcopenia
1200A: Isolated Muscle System for Mice 2018
Functional, morphological, and apoptotic alterations in skeletal muscle of ARC deficient mice. Muscle Pathology & Wasting Atrophy
2015
Isometric and eccentric force generation assessment of skeletal muscles isolated from murine models of muscular dystrophies. Muscle Pathology & Wasting Dystrophy
2013
Skeletal muscle weakness caused by carrageenan-induced inflammation. Muscle Pathology & Wasting Sarcopenia
2012
Diaphragm muscle fiber weakness in pulmonary hypertension. Muscle Pathology & Wasting Cardiovascular
1200A: Isolated Muscle System for Mice 2011
Modulation of Muscle Atrophy, Fatigue and MLC Phosphorylation by MuRF1 as Indicated by Hindlimb Suspension Studies on MuRF1-KO Mice. Muscle Pathology & Wasting Atrophy
1200A: Isolated Muscle System for Mice 2010
Fiber-type dependence of stretch-induced force enhancement in rat skeletal muscle. Exercise & Metabolism N/A
2010
Altered contractility of skeletal muscle in mice deficient in titin’s M-band region. General Physiology Myopathy
2009
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