Complete Muscle Physiology Systems
1200A: Isolated Muscle System – Mouse
The 1200A isolated muscle test system is a leading solution for quantifying mechanical properties of isolated muscle from mice. This system is ideal for a number of limb muscles including the TA, EDL, Soleus, Gastroc and for diaphragm strips and smaller muscle samples.
1205A: Isolated Muscle System – Rat
The 1205A isolated muscle test system is optimized for the study of mechanical properties of rat isolated muscle samples. Just like the 1200A, this system is ideal for a number of limb muscles such as TA, EDL, Soleus, Gastroc and for diaphragm strips and smaller muscle samples.
1300A: 3-in-1 Whole Animal System – Mouse
The 1300A is a high-performing, precise test system, giving researchers a simple method to test tensile and other mechanical properties of muscle samples from mice. By combining in-situ, in-vivo and in-vitro muscle tests using one simple platform, researchers can capture a complete picture of muscle physiology.
1305A: 3-in-1 Whole Animal System – Rat
The 1305A is a high-performing, precise test system, giving researchers a simple method to test tensile and other mechanical properties of muscle samples from Rats. By combining in-situ, in-vivo and in-vitro muscle tests using one simple platform, researchers can capture a complete picture of muscle physiology.
1310A: 3-in-1 Whole Animal System – Large Rodent & Small Animal
A flexible test system delivering accurate measurement of large rodent & small animal muscle properties in-situ, in-vivo, and in-vitro. This is ideal for live animal protocols including injury and longitudinal studies, allowing researchers to evaluate the mechanical characteristics of intact muscle of large rodents, either isolated in-situ, with a footplate (ex-vivo) or isolated in-vitro.
1400A: Permeabilized Fiber System – Microscope Mountable
The 1400A and 1410A Permeabilized Fiber Systems are designed to enhance experimental throughput and simplify complex permeabilized fiber experiments. They provide accurate measurements of fiber properties across a broad range of applications and tests.
1500A: Isolated Muscle System – Microscope Mountable
With numerous configurations, the Isolated Muscle Systems (1500A, 1510A and 1530A) are highly integrated, turnkey systems providing physiology researchers a simple way to control and measure intact muscle and physiological small tissue samples.
1600A: Permeabilized Myocyte System – Microscope Mountable
The 1600A Permeabilized Myocyte Test System is designed to streamline contractile property testing in skinned myocytes. A large cell mounting area provides ample room for cell attachment while push button controlled motorized stages simplify cell attachment to a high-speed servo motor and our 400 series precision force transducers.
1700A: Myofibril System – Microscope Mountable
The 1700A Myofibril System is the first commercially available myofibril system specifically designed to measure the nano-Newton forces arising from activation of single myofibrils. This is a complete test system, including all hardware required to characterize myofibril contraction.
Content for the Muscle Physiologist
Out of This World Research at Brock University: Space Flight’s Impact on Female Mice Reproductive Health
NASA's SpaceX CRS-29 launched on November 9th, a commercial resupply services mission to the International Space Station (ISS) that was also carrying scientific experiments and technology demonstrations. Included amongst these was the Rodent Research-20 (RR-20) payload, the contents of which will be studied by Brock University's Dr. Val Fajardo and his team using Aurora Scientific equipment upon its return.
Renewed Interests: Harnessing Engineered Constructs to Explore Novel Strategies in Regenerative Medicine
Tissue engineering is at the forefront of regenerative medicine, offering immense promise for restoring or enhancing the function of impaired tissues and organs. While tissue constructs remain costly in clinical settings, their use as a research tool holds vast potential for drug discovery, aiding and expediting the screening of drug candidates. In this publication review, we will discuss three recent publications leveraging specialized equipment from Aurora Scientific to advance the innovative field of engineered tissue constructs.
Cancer Cachexia-Induced Muscle Atrophy
Cancer cachexia is a muscle wasting syndrome that is associated with certain cancers, but most commonly with advanced malignancies. This syndrome arises as a result of tumor-induced metabolic changes, causing the body to break down skeletal muscle and adipose tissue in response to nutritional deficiencies. These changes manifest as severe weight loss, anorexia, asthenia, and anemia, impairing the patient's capacity to tolerate infections, chemotherapy, and radiation treatments (Dhanapal et al., 2022). While research characterizing the multifactorial origins of this syndrome is still ongoing, three recent publications featuring our scientific equipment have made notable advances in the current understanding of this muscle wasting disease, and are discussed in this publication review.