Complete Muscle Physiology Systems
1200A: Isolated Muscle System – Mouse
The 1200A isolated muscle test system is a leading solution for quantifying mechanical properties of isolated muscle from mice. This system is ideal for a number of limb muscles including the TA, EDL, Soleus, Gastroc and for diaphragm strips and smaller muscle samples.
1205A: Isolated Muscle System – Rat
The 1205A isolated muscle test system is optimized for the study of mechanical properties of rat isolated muscle samples. Just like the 1200A, this system is ideal for a number of limb muscles such as TA, EDL, Soleus, Gastroc and for diaphragm strips and smaller muscle samples.
1300A: 3-in-1 Whole Animal System – Mouse
The 1300A is a high-performing, precise test system, giving researchers a simple method to test tensile and other mechanical properties of muscle samples from mice. By combining in-situ, in-vivo and in-vitro muscle tests using one simple platform, researchers can capture a complete picture of muscle physiology.
1305A: 3-in-1 Whole Animal System – Rat
The 1305A is a high-performing, precise test system, giving researchers a simple method to test tensile and other mechanical properties of muscle samples from Rats. By combining in-situ, in-vivo and in-vitro muscle tests using one simple platform, researchers can capture a complete picture of muscle physiology.
1310A: 3-in-1 Whole Animal System – Large Rodent & Small Animal
A flexible test system delivering accurate measurement of large rodent & small animal muscle properties in-situ, in-vivo, and in-vitro. This is ideal for live animal protocols including injury and longitudinal studies, allowing researchers to evaluate the mechanical characteristics of intact muscle of large rodents, either isolated in-situ, with a footplate (ex-vivo) or isolated in-vitro.
1400A: Permeabilized Fiber System – Microscope Mountable
The 1400A and 1410A Permeabilized Fiber Systems are designed to enhance experimental throughput and simplify complex permeabilized fiber experiments. They provide accurate measurements of fiber properties across a broad range of applications and tests.
1500A: Isolated Muscle System – Microscope Mountable
With numerous configurations, the Isolated Muscle Systems (1500A, 1510A and 1530A) are highly integrated, turnkey systems providing physiology researchers a simple way to control and measure intact muscle and physiological small tissue samples.
1600A: Permeabilized Myocyte System – Microscope Mountable
The 1600A Permeabilized Myocyte Test System is designed to streamline contractile property testing in skinned myocytes. A large cell mounting area provides ample room for cell attachment while push button controlled motorized stages simplify cell attachment to a high-speed servo motor and our 400 series precision force transducers.
1700A: Myofibril System – Microscope Mountable
The 1700A Myofibril System is the first commercially available myofibril system specifically designed to measure the nano-Newton forces arising from activation of single myofibrils. This is a complete test system, including all hardware required to characterize myofibril contraction.
Content for the Muscle Physiologist
Tackling the Heart of the Issue: Advances in Cardiovascular Research
February notably marks “Heart Month”, aiming to highlight the importance of cardiovascular health and its critical implications on our overall wellbeing. Tackling the heart of the issue, several cardiovascular studies stand out as key players within the preclinical research landscape. The following publication review covers recent advancements in the field, including a promising therapeutic drug candidate for heart failure as well as novel insights into the cardiovascular biology of Marfan syndrome and muscle contraction regulation.
Molecular Deep Dives in Force Production
As we launch full force into 2024, studies exploring the molecular underpinnings of force production in mice have blazed the trail of functional muscular research. From calcium dynamics during muscle contraction, to muscle impairments in myotonic dystrophy, and the effects of running on muscle mass in a dystrophic mouse model, January's novel insights into muscle function and regulation have important implications on our understanding of muscle physiology and health.
Best of 2023: Across Countries and Applications
2023 has proved to be a particularly fruitful year for scientific discovery, with a multitude of pioneering studies spanning continents and disciplines. From the intricate workings of muscle physiology in Switzerland to the nuanced understanding of migraine mechanisms in the USA, the discernment of mosquito olfactory processing in India, and the innovative strides in sustainable materials science in Germany and Austria, this year's research highlights embody the spirit of global collaboration and scientific ingenuity. We hope that, by highlighting the multitude of ways our instruments provide precise and reliable data, future and current researchers can draw inspiration for new and innovative ways to collaborate across borders.