Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation.  They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

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Found 10 Results
Title Research Area Model Product Year
Engineered human myocardium with local release of angiogenic proteins improves vascularization and cardiac function in injured rat hearts Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2020
Chronic Optogenetic Pacing of Human-Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissues Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2020
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity Exercise & Metabolism Atrophy
801C: Small Intact Muscle Apparatus – Microscope Mountable 2019
Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function. Neuromuscular Cancer
801C: Small Intact Muscle Apparatus – Microscope Mountable 2015
Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes. Muscle Pathology & Wasting Myopathy
801C: Small Intact Muscle Apparatus – Microscope Mountable 2015
Timing and magnitude of systolic stretch affect myofilament activation and mechanical work. Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2014
Investigation into the cardiotoxic effects of doxorubicin on contractile function and the protection afforded by cyclosporin A using the work-loop assay. Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2014
E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction. Cardiology Myopathy
801C: Small Intact Muscle Apparatus – Microscope Mountable 2013
Ablation of cardiac myosin-binding protein-C accelerates contractile kinetics in engineered cardiac tissue. Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2013
Doxorubicin induced myocardial injury is exacerbated following ischaemic stress via opening of the mitochondrial permeability transition pore. Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2013
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