Publications

The following is a collection of select publications referencing Aurora Scientific instrumentation.  They serve as excellent examples regarding system capabilities, common research applications, methodology and best-practices.

Use the filters and settings to identify publications of interest by research application and associated Aurora Scientific system or component used.

Featured Publications

Found 10 Results
Title Research Area Disease Model System/Component Year
Engineered human myocardium with local release of angiogenic proteins improves vascularization and cardiac function in injured rat hearts Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2020
Chronic Optogenetic Pacing of Human-Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissues Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2020
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity Exercise & Metabolism Atrophy
801C: Small Intact Muscle Apparatus – Microscope Mountable 2019
Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function. Neuromuscular Cancer
801C: Small Intact Muscle Apparatus – Microscope Mountable 2015
Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes. Muscle Pathology & Wasting Myopathy
801C: Small Intact Muscle Apparatus – Microscope Mountable 2015
Timing and magnitude of systolic stretch affect myofilament activation and mechanical work. Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2014
Investigation into the cardiotoxic effects of doxorubicin on contractile function and the protection afforded by cyclosporin A using the work-loop assay. Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2014
E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction. Cardiology Myopathy
801C: Small Intact Muscle Apparatus – Microscope Mountable 2013
Ablation of cardiac myosin-binding protein-C accelerates contractile kinetics in engineered cardiac tissue. Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2013
Doxorubicin induced myocardial injury is exacerbated following ischaemic stress via opening of the mitochondrial permeability transition pore. Cardiology Cardiovascular
801C: Small Intact Muscle Apparatus – Microscope Mountable 2013
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