The 615A Dynamic Muscle Control and High-Throughput Analysis software suite (DMC/DMA-HT) combines our three LabVIEW stand-alone executable programs into one powerful and complete software package. Researchers now have an integrated software suite to handle the entire data collection, control and analysis functions of muscle contractile experiments.
The 610A Dynamic Muscle Control (DMC) LabBook software was designed to enable physiology researchers to study the dynamic mechanical characteristics of muscle tissue. The system is capable of controlling and taking data from all of our 300C series muscle levers, our 400A series of force transducers and our 700A series of stimulators.
DMC LabBook has an intuitive and easy-to-use graphical user interface that guides the user through the step-by-step process of a typical muscle mechanics experiment. Experimental data collection is highly streamlined, with prompts to enter pertinent parameters about the animal, sample and experimental protocol before data is collected, eliminating the need for handwritten lab notes. This information is easily searchable and simplifies the process of organizing data records. DMC LabBook includes a live data monitor of the current length and force to visualize real-time data output without the need to load data files.
The 611A Dynamic Muscle Analysis (DMA) software provides analysis of data recorded using the DMC program. It features an easy-to-use graphical user interface and powerful analysis functions that calculates muscle, work loop, and time-derivative data. All data can be plotted and analyzed within the program’s many windows. DMA can also be used to analyze 600A Real-Time Muscle Data Acquisition and Analysis Software data sets.
The 612A Dynamic Muscle Analysis High Throughput software (DMA-HT) is a plug-in module for DMA that automates the analysis of large data sets such as those collected when performing force-frequency, force-time, position-time or fatigue analysis experiments.
The High-throughput module automatically places cursors in your data files, calculates muscle analysis data for a list of files very quickly, then displays the results in a tabular format. The results are easily exported to Excel. Each file’s cursors can be manually adjusted afterwards, or the user can optionally disable automatic cursor placement, opting to manually set a timestamp that applies for all data files in the experiment.
three programs included in the package, 610A DMC Labbook for control and data acquisition, 611A DMA for analysis and 612A DMA-HT (high-throughput) for automated analysis of large numbers of data files
unique, searchable data management system captures all animal, muscle and study parameters
standard muscle mechanics protocols included, plus ability to create fully customizable protocols
analyze files from DMC LabBook and 600A
work loop, time derivative and line fitting modules
force-frequency, force-time, position-time and fatigue analysis included
automatically analyses hundreds of data files in seconds
Controls: Change Study, Change Animal, Sample, Prepare Experiment, Run Experiment, Analyze Results, Edit Sample Parms, View, Prev, Next, Readout 1 Select, Readout 2 Select, Reset Timer
Readouts: 1 and 22, Elapsed Time, Time since Last Test, Experiment Run Counter
Dropdown menus: File, Setup and Help
Used to define a study.
Text Entry Fields: Name of Study, Description of Study, Animal Parameter definition and selection, Sample Parameter definition and selection, Muscles in Study definition and Selection, Experiments in Study definition and selection
Select Experiment Window
Select experiments to use in a study and create new experiments
Existing Experiment list and selection button
Create New Experiment: 6 wizards to create the following experiments: Twitch, Tetanus, Fatigue, Force-Frequency, Eccentric, Injury
Custom Experiment button: opens protocol editor to allow creation of a custom experiment
Live Data Monitor
Real-time data output of chosen channels. Displays up to 30 minutes of data – zoom function, time base control, graph scales, freeze display
Prepare Experiment Window
Used to prepare the muscle for the test.
Instant Stim control, Display of Twitch Force, Overlay of successive twitches, Calculation of Baseline Force and Max Force
Load last data or saved data
Display: Length, Force, Stimulation
Plot Zoom Controls: Time Displayed and Offset sliders, Unzoom
Calculated Values: Max Force, Time of Max Force, Min Force, Time of Min Force, Force at Time Zero, Max Length, Time of Max Length, Min Length, Time of Min Length, Length at Time Zero
1 = Auxiliary Channels: can be configured to suit, common usages are: Temperature, pH, O2, etc.; 2 = Configured using Readout Select 1 and 2, normally displays Force In and Length In; 3 = Limited analysis available in 610A program, complete Analysis available in 611A and 612A programs
611A/612A DMA/DMA-HT Specifications
Display: graph of test results with zoom function
Plot Controls: Unfiltered/Filtered Force, Unfiltered/Filtered Length, Force Units, Length Units
Buttons for: Invert Force Data, Open Data File, Filter Setup, Normalization, Muscle Analysis, Work Loop, Time Derivative, Line Fitting, Export Data
Dropdown menus: File, High Throughput and Help
Filter Setup: set cutoff frequency and order of Butterworth low-pass filter
Normalization: set reference values for calculating L/Lref, F/Fref, Stress, Strain
Muscle Analysis: provides statistics of displayed data
Work Loop: calculates work loop data from sinusoidal tests
Time Derivative: calculates velocity and dF/dt
Line Fitting: fits linear or exponential functions to Force and Length data
High Throughput Analysis
Provides high speed analysis of a group of data files, data is output in tabular form and can be exported
Analysis Types: Force-Frequency, Force-Time, Position-Time, Fatigue
Calculated Values: Maximum, Minimum, Time to % Contraction, Time to % Relaxation, Integration, Max Rate of Contraction, Time to % of Max Rate of Contraction, Max Rate of Relaxation, Time to % of Max Rate of Relaxation,
Starting Baseline, Ending Baseline, Average Rate of Contraction, Average Rate of Relaxation
Exports analysis to: Excel, MATLAB, Maple, SAS, other software packages
Interested in a Dynamic Muscle Control and Analysis Software?
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