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Pain / Nociception

To understand neural responses such as pain and touch, it is necessary to apply and mimic tactile stimuli in a manner that is repeatable. Inevitable variability comes with the application of manual stimuli through the use of conventional von Frey hairs. Leading researchers in the field of nociception trust Aurora Scientific mechanical stimulators because they are versatile enough for use in a broad range of protocols and provide precise, reproducible results.

How an Animal’s Sensory System Responds to Pain and Other Tactile Stimuli

pain research, mechanical nociception, tactile discrimination, neural communication, vibrotactile stimuli

300C-I: Mechanical Stimulators - Indenter

300C-I: Mechanical Stimulators - Indenter

Automated solution that goes beyond the conventional von Frey device, with the added capability to measure and control both force and length at a single application point.

Not Available

Customized 300C-I Facilitates Migraine Headache Research

CHALLENGE

In 2002 Dr. Dan Levy of Harvard University was studying the underlying mechanisms of migraine headaches and was looking for a method to reliably apply varying forces to sensory neurons innervating the dura mater of a rat.

300C-I – Mechanical Stimulation of Rat Skin

CHALLENGE

In 1998 Dr. Woodbury approached us with a need to perform mechanical stimulation of rat skin stretched in a recording chamber. He needed a computer controlled mechanical stimulator that could produce controlled five second square waves of varying forces through a cylindrical indenter tip.

300C-I