Cardiology Archives

The 1600A permeabilized myocyte system is commonly used to investigate the active and passive properties of de-membranized cardiac myocytes. This system

Why Sarcomere Length Matters For Contractile Measurements

aursc20dev2021-11-24T15:16:54-05:00Muscle Physiology, Technical Blog|

The architecture of striated muscle consists of a number of components that work in conjunction to generate a contraction.

Commonly Used Samples and Experiments using the Myofibril System

aursc20dev2021-11-26T08:37:44-05:00Muscle Physiology, Technical Blog|

Aurora Scientific offers several different test systems to evaluate the various structural levels of muscle. However, there are many

Commonly Used Samples and Experiments using Permeabilized Myocyte Systems

aursc20dev2021-11-24T15:17:20-05:00Muscle Physiology, Technical Blog|

Aurora Scientific offers several different test systems to evaluate the various structural levels of muscle. However, there are many

Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins.

Investigation into the cardiotoxic effects of doxorubicin on contractile function and the protection afforded by cyclosporin A using the work-loop assay.

Timing and magnitude of systolic stretch affect myofilament activation and mechanical work.”

Myofilament dysfunction contributes to impaired myocardial contraction in the infarct border zone.

Automated analysis of contractile force and Ca2+ transients in engineered heart tissue.

Doxorubicin induced myocardial injury is exacerbated following ischaemic stress via opening of the mitochondrial permeability transition pore.

E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction.

Ablation of cardiac myosin-binding protein-C accelerates contractile kinetics in engineered cardiac tissue.

Deranged myofilament phosphorylation and function in experimental heart failure with preserved ejection fraction.

Deranged myofilament phosphorylation and function in experimental heart failure with preserved ejection fraction.

Ablation of cardiac myosin-binding protein-C accelerates contractile kinetics in engineered cardiac tissue.

A gain-of-function mutation in the M-domain of cardiac myosin-binding protein-C increases binding to actin.

Effects of alterations in sarcomere structure and prestretch timing on cardiac muscle mechanics.

Effect of aging on power output properties in rat skinned cardiac myocytes.

Calcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region-deficient mice.

Fabrication and evaluation of reconstructed cardiac tissue and its application to bio-actuated microdevices.

Contribution of the myosin binding protein C motif to functional effects in permeabilized rat trabeculae.

Cross-bridge interaction kinetics in rat myocardium are accelerated by strong binding of myosin to the thin filament.

Effects of thin and thick filament proteins on calcium binding and exchange with cardiac troponin C.

Fabrication and evaluation of reconstructed cardiac tissue and its application to bio-actuated microdevices.

Measuring the Mechanical Properties of Engineered Tissue Constructs

Tips and Tricks for Using the 1600A Permeabilized Myocyte System

Why Sarcomere Length Matters For Contractile Measurements

Commonly Used Samples and Experiments using the Myofibril System

Commonly Used Samples and Experiments using Permeabilized Myocyte Systems

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