825A: Thermocouple Meter / TEC Controller
The 825A Thermocouple Thermometer/TEC Controller was designed to control and measure the temperature of the Aurora Scientific physiology apparatus with accuracy and precision. Each controller works with Peltier modules to maintain the temperature of a bath in the range 0 to 40ºC within ±0.1ºC.
The 825A TEC Controller includes two LED digital displays: the right can be switched to show either Process or Setpoint temperature in ºC, the left shows measured thermocouple temperature in ºC. Setpoint is the desired temperature, while Process is the temperature measured by a temperature sensor built into the apparatus. A thermocouple thermometer is included in the 825A to allow accurate temperatures to be measured at a selected point of interest. A Physitemp microprobe T-type thermocouple is included with the 825A that can be used with the thermometer function. This probe is encapsulated in a Teflon jacket to prevent contamination of experimental fluids.
To achieve fast temperature changes with very good long-term stability the control electronics uses a proportional/integral/derivative (PID) servo control.
Variant
Temperature Jump Variant – 825A-TJ Thermocouple Meter/TEC Controller:
Temperature Jump – Modified 825 for control of baths 1 and 2 on 802D-TJ Permeabilized Fiber Temperature Jump Apparatus
Select References
- Malfatti, Edoardo et al. “Muscle histopathology in nebulin-related nemaline myopathy: ultrastrastructural findings correlated to disease severity and genotype.” Acta Neuropathologica Communications (2014) DOI: 10.1186/2051-5960-2-44
- DeWinter, Josine M. et al. “Effect of levosimendan on the contractility of muscle fibers from nemaline myopathy patients with mutations in the nebulin gene.” Skeletal Muscle (2015) DOI: 10.1186/s13395-015-0037-7
- Hamdi, Muhammad M. and Gabriel Mutungi. “Dihydrotestosterone activates the MAPK pathway and modulates maximum isometric force through the EGF receptor in isolated intact mouse skeletal muscle fibres.” The Journal of Physiology (2010) DOI: 10.1113/jphysiol.2009.182162
- McCormick, Cecilia et al. “Clenbuterol and formoterol decrease force production in isolated intact mouse skeletal muscle fiber bundles through a beta2-adrenoceptor-independent mechanism.” Journal of Applied Physiology (2010) DOI: 10.1152/japplphysiol.00592.2010
- Gineste, Charlotte, et al. “Alterations at the Cross-Bridge Level Are Associated with a Paradoxical Gain of Muscle Function In Vivo in a Mouse Model of Nemaline Myopathy.” PLoS ONE (2014) DOI: 10.1371/journal.pone.0109066
- Norden, Diana M. et al “Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function.” Brain, Behavior, and Immunity (2015) DOI: 10.1016/j.bbi.2014.07.013
- Tangney, Jared R. et al. “Timing and magnitude of systolic stretch affect myofilament activation and mechanical work.” American Journal of Physiology-Heart and Circulatory Physiology (2014) DOI: 10.1152/ajpheart.00233.2014
- Raval, Kunil K. et al. “Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes.” The Journal of Biological Chemistry (2015) DOI: 10.1074/jbc.M114.628628
- Heden et al. “Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity” Science Advances (2019) DOI: 10.1126/sciadv.aax8352
- Gharanei, Mayel “Investigation into the cardiotoxic effects of doxorubicin on contractile function and the protection afforded by cyclosporin A using the work-loop assay.” Toxicology in Vitro (2014) DOI: 10.1016/j.tiv.2014.01.011
Related Products
801C: Small Intact Muscle Apparatus – Microscope Mountable
Highly integrated apparatus, optimally designed to test small, intact muscle contractility
Learn More
802D: Permeabilized Fiber Apparatus – Microscope Mountable
A multi-well automated test system for quick and accurate measurement of permeabilized fiber dynamics
Learn More
803B: Permeabilized Myocyte Apparatus – Microscope Mountable
Innovative 8–well plate designed for quick cell attachment and measurement of myocyte mechanical properties
Learn More
804A: Permeabilized Fiber ATPase Apparatus
The 804A ATPase apparatus was designed to enable physiology researchers to measure consumption of ATP along with contractile force and length changes of permeabilized fibers. The 804A works in conjunction with an Aurora Scientific model 315D or 322D high-speed length controller and an Aurora 400C series force transducer.
Learn MoreSpecifications
| Temperature Control | 825A |
|---|---|
| Output Voltage [V] | 12 VDC |
| Output Current [A] | ± 3.5 (max) |
| Control Range | 0 – 40°C |
| Set Point Control | 10-turn Dial |
| Control Loop | Proportional/Integral/Derivative (PID) |
| Digital Display [°C] | Set Point/Feedback Temperature (switch selectable) |
| Output Connector | 6-pin mini DIN |
| Thermocouple Thermometer | 825A |
|---|---|
| Type | T |
| Temperature Range [°C] | -50 to +50 |
| Temperature Accuracy [°C] | ± 0.5, @ 0 to +40 |
| Output Voltage [mV/°C] | 10 |
| Input Connector | Miniature T-type |
| Output Connector | BNC |
| Digital Display [°C] | Thermocouple Temperature |
| Power Required | 9 VDC battery, 3mA maximum |
| Thermoelectric Module | 825A |
|---|---|
| Number of TECs | 2 |
| Power [W] | 33 |
| Voltage [V] | 12 |
| General Specifications | 825A |
|---|---|
| Power Required | 100, 120, 220, 240 VAC, 50/60 Hz. available |
| Weight [kg] | 3.1 |
| Dimensions [cm] | 21W (1/2 rack mount) x 25D x 9H (2U) |