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300C-I: Mechanical Stimulators – Indenter

The 300C-I mechanical stimulator is an automated electronic von Frey device with the added capability to measure and control both force and length at a single application point. The 300C-I takes the variability and awkwardness out of applying force with a handheld von Frey filament or with other handheld mechanical stimulators. Our computer-controlled mechanical stimulator removes the unavoidable hand tremor associated with both von Frey filaments and other electronic von Frey systems. This removes the associated variation in force application.

Aurora Scientific’s mechanical stimulator increases throughput by eliminating the need for multiple tests to determine threshold. The force application and timing of the stimulus is consistent and precise, thereby removing the variability associated with handheld devices.

The mechanical stimulator is capable of applying constant force for pre-set periods of time with the added functionality of adjusting force at pre-determined rates. Stimulation can be applied in any combination of length or force and can follow an arbitrary force or distance application curve so force application is not limited to simple force ramps.

The delivery of constant and repeatable force ensures that consistency is maintained between experiments, subjects and studies, thus reducing avoidable error in your data and improving the quality of your findings.

None

  • quantify mechanosensitivity using computer-controlled stimuli
  • evaluate the suprathreshold mechanosensitivity
  • measure the mechanical threshold without performing multiple tests
  • force ranges: 0.5N – 10N
  • superior resolution (to 0.3mN)
  • operates in any orientation
  • minimizes off-axis forces
  • range of tips available (0.5, 0.8, 1, 1.5, 2, 3 mm diameter)
  • application area remains constant over full range of force

Customized 300C-I Facilitates Migraine Headache Research

CHALLENGE

In 2002 Dr. Dan Levy of Harvard University was studying the underlying mechanisms of migraine headaches and was looking for a method to reliably apply varying forces to sensory neurons innervating the dura mater of a rat.

300C-I – Mechanical Stimulation of Rat Skin

CHALLENGE

In 1998 Dr. Woodbury approached us with a need to perform mechanical stimulation of rat skin stretched in a recording chamber. He needed a computer controlled mechanical stimulator that could produce controlled five second square waves of varying forces through a cylindrical indenter tip.

Models In The Series

300C-I: Dual-Mode Indenter, 0.5N Force, 10mm Excursion

Seamless, flexible control of indentation force and length, with the unique ability to measure one or both in a single mechanical stimulator

300C-LR-I: Dual-Mode Indenter, 1N Force, 10mm Excursion

Seamless, flexible control of indentation force and length, with the unique ability to measure one or both in a single mechanical stimulator

305C-I: Dual-Mode Indenter, 5N Force, 20mm Excursion

Seamless, flexible control of indentation force and length, with the unique ability to measure one or both in a single mechanical stimulator

305C-LR-I: Dual-Mode Indenter, 10N Force, 20mm Excursion
Seamless, flexible control of indentation force and length, with the unique ability to measure one or both in a single mechanical stimulator