825B: TEC Controller / Thermometer
The 825B TEC Controller / Thermometer was designed to control and measure the temperature of the Aurora Scientific physiology apparatus with accuracy and precision. Each controller works with Peltier modules to maintain the temperature of a bath in the range of 0 to 40ºC within ±0.1ºC.
The 825B TEC Controller includes an LED digital display that can be switched to show Set Point temperature, Process temperature or Sensor temperature measured in ºC. Setpoint is the desired temperature, while Process is the temperature measured by a temperature sensor built into the apparatus. A thermistor-based thermometer is included in the 825B to allow accurate temperatures to be measured at a point of interest. A thermistor microprobe is included with the 825B that can be used with the thermometer function. This probe is encapsulated in a Teflon jacket to prevent contamination of experimental fluids.
To achieve fast temperature changes with very good long-term stability the control electronics uses a microprocessor running a proportional/integral/derivative (PID) control algorithm.
Variant
Temperature Jump Variant – 825B-TJ TEC Controller / Thermometer:
Temperature Jump TEC Controller – Modified 825 for control of baths 1 and 2 on 802D-TJ Permeabilized Fiber Temperature Jump Apparatus
Select References
- Malfatti, Edoardo et al. “Muscle histopathology in nebulin-related nemaline myopathy: ultrastrastructural findings correlated to disease severity and genotype.” Acta Neuropathologica Communications (2014) DOI: 10.1186/2051-5960-2-44
- DeWinter, Josine M. et al. “Effect of levosimendan on the contractility of muscle fibers from nemaline myopathy patients with mutations in the nebulin gene.” Skeletal Muscle (2015) DOI: 10.1186/s13395-015-0037-7
- Hamdi, Muhammad M. and Gabriel Mutungi. “Dihydrotestosterone activates the MAPK pathway and modulates maximum isometric force through the EGF receptor in isolated intact mouse skeletal muscle fibres.” The Journal of Physiology (2010) DOI: 10.1113/jphysiol.2009.182162
- McCormick, Cecilia et al. “Clenbuterol and formoterol decrease force production in isolated intact mouse skeletal muscle fiber bundles through a beta2-adrenoceptor-independent mechanism.” Journal of Applied Physiology (2010) DOI: 10.1152/japplphysiol.00592.2010
- Karimi et al. “Characterization of NEB pathogenic variants in patients reveals novel nemaline myopathy disease mechanisms and omecamtiv mecarbil force effects” Acta Neuropathol (2024) DOI: 10.1007/s00401-024-02726-w
- Gineste, Charlotte, et al. “Alterations at the Cross-Bridge Level Are Associated with a Paradoxical Gain of Muscle Function In Vivo in a Mouse Model of Nemaline Myopathy.” PLoS ONE (2014) DOI: 10.1371/journal.pone.0109066
- Norden, Diana M. et al “Tumor growth increases neuroinflammation, fatigue and depressive-like behavior prior to alterations in muscle function.” Brain, Behavior, and Immunity (2015) DOI: 10.1016/j.bbi.2014.07.013
- Tangney, Jared R. et al. “Timing and magnitude of systolic stretch affect myofilament activation and mechanical work.” American Journal of Physiology-Heart and Circulatory Physiology (2014) DOI: 10.1152/ajpheart.00233.2014
- Raval, Kunil K. et al. “Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes.” The Journal of Biological Chemistry (2015) DOI: 10.1074/jbc.M114.628628
- Heden et al. “Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity” Science Advances (2019) DOI: 10.1126/sciadv.aax8352
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Learn MoreSpecifications
| Temperature Control | 825B |
|---|---|
| Output Voltage [VDC] | 12 |
| Output Current [A] | ± 6.0 |
| Feedback Sensor1 | 10K NTC Thermistor or AD590 |
| Control Range [°C] | 0 – 40°C |
| Temperature Stability [°C] | ±0.1 |
| Set Point Control | Front panel, 10-turn, 4°C/turn |
| Control Loop | Proportional/Integral/Derivative (PID) |
| Warm up Time [minutes] | 10 |
| LED Display (switch selectable) [°C] | Sensor (micro-probe thermistor sensor temperature)
Process (bath plate temperature) Set Point (desired temperature) |
| TEC Connector | 6-pin mini DIN |
1 Jumper selectable within controller
| General Specifications | 825B |
|---|---|
| Operating Temperature [°C] | 10 – 30 |
| Power Required | 100, 120, 220, 240 VAC, 50/60 Hz. available |
| Power Consumption [W] | 100 |
| Fuse Type | 250V Time Delay, IEC 127-III: 5x20mm |
| Fuse Rating | 110/125VAC – T 2.0A
220/240VAC – T 1.0A |
| Weight [kg] | 3.1 |
| Dimensions [cm] | 9H (2U) x 21W (1/2 rack) x 25D |
| Thermistor Micro-Probe Thermometer | 825B |
|---|---|
| Type | Thermistor, NTC 10K 3984K |
| Temperature Range [°C] | -55 to +125 |
| Temperature Accuracy [°C] | ± 0.1, 0 to 40 |
| Output Voltage [mV/°C] | 10 |
| Sensor Connector | 2.5mm mono |
| Sensor Out Connector | BNC |
| Sensor Out Scale Factor [mV/°C] | 100, (0.00 V = 0°C) |
| Thermoelectric Module | 825B |
|---|---|
| Number of TECs | 2 |
| Power [W] | 33 |
| Voltage [V] | 15 |