FEATURED POST
READ: Aurora Scientific Joins Lafayette Instrument Company to Enhance Scientific Research Offerings!
We are pleased to announce that Aurora Scientific Inc. has been acquired on April 17, 2023 by Lafayette Instrument Company and is now a wholly owned subsidiary thereof. The acquisition brings together two leading companies with decades of experience in their respective specialties of life science.
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Featured Articles
Tackling the Heart of the Issue: Advances in Cardiovascular Research
February notably marks “Heart Month”, aiming to highlight the importance of cardiovascular health and its critical implications on our overall wellbeing. Tackling the heart of the issue, several cardiovascular studies stand out as key players within the preclinical research landscape. The following publication review covers recent advancements in the field, including a promising therapeutic drug candidate for heart failure as well as novel insights into the cardiovascular biology of Marfan syndrome and muscle contraction regulation.
Molecular Deep Dives in Force Production
As we launch full force into 2024, studies exploring the molecular underpinnings of force production in mice have blazed the trail of functional muscular research. From calcium dynamics during muscle contraction, to muscle impairments in myotonic dystrophy, and the effects of running on muscle mass in a dystrophic mouse model, January's novel insights into muscle function and regulation have important implications on our understanding of muscle physiology and health.
2024 Spring/Summer Scientific Conferences and Meetings
The Aurora Scientific team is continuing to journey out and connect with researchers at scientific conferences and meetings all over the world this spring and summer! We are particularly thrilled to be able to meet face-to-face with you all.
News & Events
Out of This World Research at Brock University: Space Flight’s Impact on Female Mice Reproductive Health
NASA's SpaceX CRS-29 launched on November 9th carrying the Rodent Research-20 (RR-20) payload, the contents of which will be studied by Brock University's Dr. Val Fajardo and his team using Aurora Scientific equipment upon its return.
Cut and Paste of Myosin Binding Protein-C in Striated Muscles
Dr. Samantha Harris discusses the development of three new mouse models in her lab, engineered to target and replace specific myosin binding protein-C paralogs in muscle fibers and impact of their mutations on skeletal and cardiac muscle diseases.
Integrating Patient Engagement and Trainee Development in Pre-Clinical Research
Christopher Perry, PhD discusses how his laboratory aims to discover mechanisms by which metabolic dysfunction causes muscle weakness and apply these findings to develop new therapies for muscle disorders. Homira Osman, PhD will provide a particular focus on leveraging scientific findings for practice and policy and linking trainees with patient communities.
Muscle Physiology
Renewed Interests: Harnessing Engineered Constructs to Explore Novel Strategies in Regenerative Medicine
Tissue engineering is at the forefront of regenerative medicine, offering immense promise for restoring or enhancing the function of impaired tissues and organs. While tissue constructs remain costly in clinical settings, their use as a research tool holds vast potential for drug discovery, aiding and expediting the screening of drug candidates. In this publication review, we will discuss three recent publications leveraging specialized equipment from Aurora Scientific to advance the innovative field of engineered tissue constructs.
Cancer Cachexia-Induced Muscle Atrophy
Cancer cachexia is a muscle wasting syndrome that is associated with certain cancers, but most commonly with advanced malignancies. This syndrome arises as a result of tumor-induced metabolic changes, causing the body to break down skeletal muscle and adipose tissue in response to nutritional deficiencies. These changes manifest as severe weight loss, anorexia, asthenia, and anemia, impairing the patient's capacity to tolerate infections, chemotherapy, and radiation treatments (Dhanapal et al., 2022). While research characterizing the multifactorial origins of this syndrome is still ongoing, three recent publications featuring our scientific equipment have made notable advances in the current understanding of this muscle wasting disease, and are discussed in this publication review.
Recent Therapeutic Advances in Duchenne Muscular Dystrophy (DMD) Models
The following publication review showcases recent studies focused on therapeutic advances in Duchenne Muscular Dystrophy (DMD) that use Aurora Scientific equipment.
Cut and Paste of Myosin Binding Protein-C in Striated Muscles
Dr. Samantha Harris discusses the development of three new mouse models in her lab, engineered to target and replace specific myosin binding protein-C paralogs in muscle fibers and impact of their mutations on skeletal and cardiac muscle diseases.
Integrating Patient Engagement and Trainee Development in Pre-Clinical Research
Christopher Perry, PhD discusses how his laboratory aims to discover mechanisms by which metabolic dysfunction causes muscle weakness and apply these findings to develop new therapies for muscle disorders. Homira Osman, PhD will provide a particular focus on leveraging scientific findings for practice and policy and linking trainees with patient communities.
Analyzing Cardiac Tissue Function
The following publication review showcases recent studies that use Aurora Scientific equipment to make advances in the field of biomechanics.
The Latest in Biomechanics
The following publication review showcases recent studies that use Aurora Scientific equipment to make advances in the field of biomechanics.
Exercise Science
Aurora Scientific equipment has played important roles in helping researchers understand muscle physiology under a variety of conditions in animal models as highlighted in this publication review.
Olfaction & Plume Tracking
Best of 2021: Neuroscience – Olfaction and Somatosensation
Spatial arrangement of Ret+ and TrkB+ Meissner afferent cutaneous endings. Image courtesy of Neubarth et al., 2020. This publication review
How to Calibrate a 200B miniPID Using the Simple Gas Mixing Technique
The 200B miniPID is a fast response gas sensor commonly used in olfaction research as a validation tool to ensure a repeatable odor profile is
Tips and Tricks for Troubleshooting the 200B miniPID
Here we will cover some of the more common issues that researchers encounter when using our miniPID Fast Response Olfaction Sensor. If you encounter an issue
Pain & Nociception
Identification and Classification of Tongue-Innervating Mechanoreceptors
Join Yalda Moayedi, PhD, for a discussion on how tongue-innervating neurons can be clearly identified and classified according to their mechanosensory functionalities.
Best of 2021: Neuroscience – Olfaction and Somatosensation
Spatial arrangement of Ret+ and TrkB+ Meissner afferent cutaneous endings. Image courtesy of Neubarth et al., 2020. This publication review
Tips and Tricks for Troubleshooting the 300C Dual-Mode Muscle Levers
Here we will cover some of the more common issues that researchers encounter when using our Dual-Mode Lever System. If you encounter an issue with your
Materials Science
Best of 2021: Material Science
This publication review summarizes some of the best recent articles that fall under our Material Science category.
How to calibrate an Aurora Scientific High Speed Length Controller using HVSL
Our 315D & 322D models of High-Speed Length Controllers are routinely used by researchers studying small tissue samples such as fibers and cells because these
Measuring the Mechanical Properties of Engineered Tissue Constructs
Tissue engineering is an important field of regenerative medicine for tissue repair after damage caused by disease or physical trauma. Stem cells