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Cardiology

For nearly 20 years Aurora Scientific has been at the forefront of cardiac tissue mechanics research. Aurora Scientific equipment is used by many of the world’s top researchers studying isolated heart tissue, fibers and even cells. We understand that heart muscle is different from other types of muscle and that its study presents unique challenges. Whether measuring force in cardiac myocytes or quantifying the mechanical properties of iPSC-derived cardiac scaffolds, Aurora Scientific has the expertise and the instruments to support the most demanding of cardiac mechanics experiments.

The Study Of Heart Muscle Tissue and How to Preserve It

myosin thick & thin filaments, myofibrillar protein function, cardiac scaffolds & constructs, induced pluripotent stem cells (iPSC)-derived cardiomyocytes, cross -bridge cycling kinetics, artificial cardiac constructs, cardiac tissue engineering

1500A: Isolated Muscle System - Microscope Mountable

1500A: Isolated Muscle System - Microscope Mountable

Measure complete mechanical properties of small samples with a turnkey system for intact muscle and physiological tissues.
1400A: Permeabilized Fiber System - Microscope Mountable

1400A: Permeabilized Fiber System - Microscope Mountable

Simplify your most demanding permeabilized fiber experiments with a revolutionary automatic indexing test system.
1600A: Permeabilized Myocyte System - Microscope Mountable

1600A: Permeabilized Myocyte System - Microscope Mountable

Reliable and repeatable test system for measuring passive and active properties of permeabilized myocytes.

Dr. Frank Brozovich – Mayo Clinic, Rochester

I have used Aurora Scientific equipment in my laboratory for over 15 years, and there is no question that it just works, day after day. Aurora Scientific’s expertise is reflected in the easy to use platform that is truly plug and play. Over the years, I have recommended Aurora to many colleagues, and no one has been disappointed.

1400A – Durable System Helps Researcher Study Thousands of Fibers

CHALLENGE

In 2004, Dr. Hans Degens was studying changes in skeletal muscle function and morphology. Dr. Degens was looking to use permeabilized fibers as his test samples as they represent a pure system for studying cross-bridge mechanics without bias and artifacts.

950A – Software Module Helps Synchronize Cutting-Edge Data in Myocyte Research

CHALLENGE

In late 2013 Dr. Chris Ward of the University of Maryland was working on improving experimental techniques for measuring force, SL and calcium release in single, living myocytes from the FDB muscle.

801C – Ability to Assess Oxygen Consumption/Customization

CHALLENGE

In 2008 Dr. Carter Ralphe at the University of Wisconsin was attempting to measure force and contractility in his tissue constructs in an oxygen sealed environment.

1600A – Turnkey Solution Aids Characterization of Cardiac Cell Mechanics in Heart Failure

CHALLENGE

Dr. Jonathan Kirk was working as a postdoctoral fellow in Dr. David Kass’ lab at Johns Hopkins University who had acquired his own custom built equipment for testing mechanics of heart failure in skinned cardiomyocytes.

1400A

1500A

1600A